Neurotransmitters serve as chemical messengers playing a crucial role in information
processing throughout the nervous system, and are essential for healthy physiological and …

Serotonin (5-hydroxytryptamine, 5-HT) is acknowledged as a major neuromodulator of
nervous systems in both invertebrates and vertebrates. It has been proposed for several …

The human social brain is complex. Current knowledge fails to define the neurobiological
processes underlying social behaviour involving the (patho-) physiological mechanisms that …

L-5-hydroxytryptophan (5-HTP) is both a drug and a natural component of some dietary
supplements. 5-HTP is produced from tryptophan by tryptophan hydroxylase (TPH), which is …

Background: Psilocybin, a psychoactive serotonin receptor partial agonist, has been
reported to acutely reduce clinical symptoms of depressive disorders. Psilocybin's effects on …

The gut microbiome has been linked to fear extinction learning in animal models. Here, we
aimed to explore the gut microbiome and memory domains according to obesity status. A …

Understanding the underlying mechanisms of the human brain in health and disease will
require models with necessary and sufficient details to explain how function emerges from …

Neonicotinoids are a class of insecticides that exert their effect through a specific action on
neuronal nicotinic acetylcholine receptors (nAChRs). The success of these insecticides is …

Background Despite advances in research on neurodegenerative diseases, the
pathogenesis and treatment response of neurodegenerative diseases remain unclear …

Alzheimer's disease (AD) is the primary cause of dementia and is characterized by the death
of brain cells due to the accumulation of insoluble amyloid plaques, hyperphosphorylation of …