Inflammatory molecules might become both biomarkers and therapeutic targets for stroke management
L Ramiro, A Simats… - Therapeutic …, 2018 - journals.sagepub.com
Stroke is the fifth leading cause of death and the most frequent cause of disability worldwide.
Currently, stroke diagnosis is based on neuroimaging; therefore, the lack of a rapid tool to …
Currently, stroke diagnosis is based on neuroimaging; therefore, the lack of a rapid tool to …
In vitro oxygen glucose deprivation model of ischemic stroke: a proteomics-driven systems biological perspective
Oxygen glucose deprivation (OGD) of brain cells is the commonest in vitro model of ischemic
stroke that is used extensively for basic and preclinical stroke research. Protein mass …
stroke that is used extensively for basic and preclinical stroke research. Protein mass …
Reactive astrocytic S1P3 signaling modulates the blood–tumor barrier in brain metastases
B Gril, AN Paranjape, S Woditschka, E Hua… - Nature …, 2018 - nature.com
Brain metastases are devastating complications of cancer. The blood–brain barrier (BBB),
which protects the normal brain, morphs into an inadequately characterized blood–tumor …
which protects the normal brain, morphs into an inadequately characterized blood–tumor …
The Group B Streptococcal surface antigen I/II protein, BspC, interacts with host vimentin to promote adherence to brain endothelium and inflammation during the …
L Deng, BL Spencer, JA Holmes, R Mu, S Rego… - PLoS …, 2019 - journals.plos.org
Streptococcus agalactiae (Group B Streptococcus, GBS) normally colonizes healthy adults
but can cause invasive disease, such as meningitis, in the newborn. To gain access to the …
but can cause invasive disease, such as meningitis, in the newborn. To gain access to the …
Lucifer yellow-a robust paracellular permeability marker in a cell model of the human blood-brain barrier
The blood-brain barrier BBB consists of endothelial cells that form a barrier between the
systemic circulation and the brain to prevent the exchange of non-essential ions and toxic …
systemic circulation and the brain to prevent the exchange of non-essential ions and toxic …
sTWEAK is a leukoaraiosis biomarker associated with neurovascular angiopathy
A da Silva‐Candal, A Custodia… - Annals of Clinical …, 2022 - Wiley Online Library
Objective Leukoaraiosis (LA) refers to white matter lesions of undetermined etiology
associated with the appearance and worsening of vascular pathologies. The aim is to …
associated with the appearance and worsening of vascular pathologies. The aim is to …
Characterization of a two-component system transcriptional regulator, LtdR, that impacts group B streptococcal colonization and disease
L Deng, R Mu, TA Weston, BL Spencer… - Infection and …, 2018 - Am Soc Microbiol
Streptococcus agalactiae (group B Streptococcus [GBS]) is often a commensal bacterium
that colonizes healthy adults asymptomatically and is a frequent inhabitant of the vaginal …
that colonizes healthy adults asymptomatically and is a frequent inhabitant of the vaginal …
Role of PATJ in stroke prognosis by modulating endothelial to mesenchymal transition through the Hippo/Notch/PI3K axis
A Medina-Dols, G Cañellas, T Capó, M Solé… - Cell death …, 2024 - nature.com
Through GWAS studies we identified PATJ associated with functional outcome after
ischemic stroke (IS). The aim of this study was to determine PATJ role in brain endothelial …
ischemic stroke (IS). The aim of this study was to determine PATJ role in brain endothelial …
Grapevine–downy mildew rendezvous: Proteome analysis of the first hours of an incompatible interaction
R B. Santos, R Nascimento, A V. Coelho, A Figueiredo - Plants, 2020 - mdpi.com
Grapevine is one of the most relevant crops in the world being used for economically
important products such as wine. However, relevant grapevine cultivars are heavily affected …
important products such as wine. However, relevant grapevine cultivars are heavily affected …
Reprogramming of lipid metabolism as a new driving force behind tauroursodeoxycholic acid-induced neural stem cell proliferation
MB Fernandes, M Costa, MF Ribeiro… - Frontiers in Cell and …, 2020 - frontiersin.org
Recent evidence suggests that neural stem cell (NSC) fate is highly dependent on
mitochondrial bioenergetics. Tauroursodeoxycholic acid (TUDCA), an endogenous …
mitochondrial bioenergetics. Tauroursodeoxycholic acid (TUDCA), an endogenous …