Natural and targeted circuit reorganization after spinal cord injury

MA Anderson, JW Squair, M Gautier, TH Hutson… - Nature …, 2022 - nature.com
A spinal cord injury disrupts communication between the brain and the circuits in the spinal
cord that regulate neurological functions. The consequences are permanent paralysis, loss …

Quantitative magnetic resonance imaging of brain anatomy and in vivo histology

N Weiskopf, LJ Edwards, G Helms… - Nature Reviews …, 2021 - nature.com
Quantitative magnetic resonance imaging (qMRI) goes beyond conventional MRI, which
aims primarily at local image contrast. It provides specific physical parameters related to the …

Spinal cord repair: advances in biology and technology

G Courtine, MV Sofroniew - Nature medicine, 2019 - nature.com
Individuals with spinal cord injury (SCI) can face decades with permanent disabilities.
Advances in clinical management have decreased morbidity and improved outcomes, but …

The neuroanatomical–functional paradox in spinal cord injury

K Fouad, PG Popovich, MA Kopp… - Nature Reviews …, 2021 - nature.com
Although lesion size is widely considered to be the most reliable predictor of outcome after
CNS injury, lesions of comparable size can produce vastly different magnitudes of functional …

[HTML][HTML] hMRI–A toolbox for quantitative MRI in neuroscience and clinical research

K Tabelow, E Balteau, J Ashburner, MF Callaghan… - Neuroimage, 2019 - Elsevier
Neuroscience and clinical researchers are increasingly interested in quantitative magnetic
resonance imaging (qMRI) due to its sensitivity to micro-structural properties of brain tissue …

Acute and non-resolving inflammation associate with oxidative injury after human spinal cord injury

T Zrzavy, C Schwaiger, I Wimmer, T Berger, J Bauer… - Brain, 2021 - academic.oup.com
Traumatic spinal cord injury is a devastating insult followed by progressive cord atrophy and
neurodegeneration. Dysregulated or non-resolving inflammatory processes can disturb …

Traumatic and nontraumatic spinal cord injury: pathological insights from neuroimaging

G David, S Mohammadi, AR Martin… - Nature Reviews …, 2019 - nature.com
Pathophysiological changes in the spinal cord white and grey matter resulting from injury
can be observed with MRI techniques. These techniques provide sensitive markers of …

Progressive inflammation‐mediated neurodegeneration after traumatic brain or spinal cord injury

AI Faden, J Wu, BA Stoica… - British journal of …, 2016 - Wiley Online Library
Traumatic brain injury (TBI) has been linked to dementia and chronic neurodegeneration.
Described initially in boxers and currently recognized across high contact sports, the …

MRI in traumatic spinal cord injury: from clinical assessment to neuroimaging biomarkers

P Freund, M Seif, N Weiskopf, K Friston… - The Lancet …, 2019 - thelancet.com
Traumatic spinal cord injury occurs when an external physical impact damages the spinal
cord and leads to permanent neurological dysfunction and disability, and it is associated …

[HTML][HTML] Widespread age-related differences in the human brain microstructure revealed by quantitative magnetic resonance imaging

MF Callaghan, P Freund, B Draganski, E Anderson… - Neurobiology of …, 2014 - Elsevier
A pressing need exists to disentangle age-related changes from pathologic
neurodegeneration. This study aims to characterize the spatial pattern and age-related …