Pharmacological agents for adults with acute respiratory distress syndrome
SR Lewis, MW Pritchard, CM Thomas… - Cochrane Database of …, 2019 - cochranelibrary.com
Background Acute respiratory distress syndrome (ARDS) is a life‐threatening condition
caused by direct or indirect injury to the lungs. Despite improvements in clinical …
caused by direct or indirect injury to the lungs. Despite improvements in clinical …
Acute respiratory distress syndrome
R Mac Sweeney, DF McAuley - The Lancet, 2016 - thelancet.com
Acute respiratory distress syndrome presents as hypoxia and bilateral pulmonary infiltrates
on chest imaging in the absence of heart failure sufficient to account for this clinical state …
on chest imaging in the absence of heart failure sufficient to account for this clinical state …
[HTML][HTML] Vitamin D deficiency contributes directly to the acute respiratory distress syndrome (ARDS)
Rationale Vitamin D deficiency has been implicated as a pathogenic factor in sepsis and
intensive therapy unit mortality but has not been assessed as a risk factor for acute …
intensive therapy unit mortality but has not been assessed as a risk factor for acute …
Alveolar type 2 progenitor cells for lung injury repair
AM Olajuyin, X Zhang, HL Ji - Cell death discovery, 2019 - nature.com
Alveolar type 2 progenitor cells (AT2) seem closest to clinical translation, specifying the
evidence that AT2 may satisfactorily control the immune response to decrease lung injury by …
evidence that AT2 may satisfactorily control the immune response to decrease lung injury by …
Central roles of NLRs and inflammasomes in viral infection
TD Kanneganti - Nature Reviews Immunology, 2010 - nature.com
The immune response to viral infections is determined by a complex interplay between the
pathogen and the host. Innate immune cells express a set of cytosolic sensors to detect viral …
pathogen and the host. Innate immune cells express a set of cytosolic sensors to detect viral …
Effect of intravenous β-2 agonist treatment on clinical outcomes in acute respiratory distress syndrome (BALTI-2): a multicentre, randomised controlled trial
Background In a previous randomised controlled phase 2 trial, intravenous infusion of
salbutamol for up to 7 days in patients with acute respiratory distress syndrome (ARDS) …
salbutamol for up to 7 days in patients with acute respiratory distress syndrome (ARDS) …
The β-Agonist Lung Injury Trial (BALTI) a randomized placebo-controlled clinical trial
GD Perkins, DF McAuley, DR Thickett… - American journal of …, 2006 - atsjournals.org
Rationale: Experimental data suggest that manipulation of alveolar fluid clearance with β-
agonists can accelerate the resolution of alveolar edema and improve survival. Objective: To …
agonists can accelerate the resolution of alveolar edema and improve survival. Objective: To …
[HTML][HTML] Acute respiratory distress syndrome: pathophysiology and therapeutic options
C Pierrakos, M Karanikolas, S Scolletta… - Journal of clinical …, 2012 - ncbi.nlm.nih.gov
Abstract Acute Respiratory Distress Syndrome (ARDS) is a common entity in critical care.
ARDS is associated with many diagnoses, including trauma and sepsis, can lead to multiple …
ARDS is associated with many diagnoses, including trauma and sepsis, can lead to multiple …
Epigenetic regulation of angiotensin-converting enzyme 2 (ACE2) by SIRT1 under conditions of cell energy stress
NE Clarke, ND Belyaev, DW Lambert… - Clinical Science, 2014 - portlandpress.com
ACE2 (angiotensin-converting enzyme 2) counterbalances the actions of ACE (angiotensin-
converting enzyme) by metabolizing its catalytic product, the vasoactive and fibrogenic …
converting enzyme) by metabolizing its catalytic product, the vasoactive and fibrogenic …
Inflammation and fibrosis during Chlamydia pneumoniae infection is regulated by IL-1 and the NLRP3/ASC inflammasome
X He, S Mekasha, N Mavrogiorgos… - The Journal of …, 2010 - journals.aai.org
Chlamydia pneumoniae is a common respiratory pathogen associated with atypical
pneumonia, and it has been suggested as a trigger or promoter of several chronic …
pneumonia, and it has been suggested as a trigger or promoter of several chronic …