HTLV-1-associated myelopathy/tropical spastic paraparesis

CRM Bangham, A Araujo, Y Yamano… - Nature reviews Disease …, 2015 - nature.com
Human T-lymphotropic virus 1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis
(HAM/TSP) is a progressive disease of the CNS that causes weakness or paralysis of the …

Novel insights into human T‐lymphotropic virus type‐1 (HTLV‐1) pathogenesis‐host interactions in the manifestation of HTLV‐1‐associated myelopathy/tropical …

S Ahmadi Ghezeldasht, A Mosavat… - Reviews in Medical …, 2024 - Wiley Online Library
Human T‐lymphotropic virus type‐1 (HTLV‐1) was the first discovered human oncogenic
retrovirus, the etiological agent of two serious diseases have been identified as adult T‐cell …

[HTML][HTML] Refining the risk of HTLV-1-associated myelopathy in people living with HTLV-1: identification of a HAM-like phenotype in a proportion of asymptomatic …

D Harding, C Rosadas, SM Tsoti, A Heslegrave… - Journal of …, 2022 - Springer
Abstract Up to 3.8% of human T-lymphotropic virus type-1 (HTLV-1)-infected asymptomatic
carriers (AC) eventually develop HTLV-1-associated myelopathy (HAM). HAM occurs in …

[HTML][HTML] Ciclosporin A proof of concept study in patients with active, progressive HTLV-1 associated myelopathy/tropical spastic paraparesis

F Martin, H Castro, C Gabriel, A Adonis… - PLoS neglected …, 2012 - journals.plos.org
Introduction Patients with HTLV-1-associated myelopathy/tropical spastic paraparesis
(HAM/TSP) become progressively impaired, with chronic pain, immobility and bladder …

Human T-cell leukemia/lymphoma virus type 1 p30, but not p12/p8, counteracts toll-like receptor 3 (TLR3) and TLR4 signaling in human monocytes and dendritic cells

C Fenizia, M Fiocchi, K Jones, RW Parks… - Journal of …, 2014 - Am Soc Microbiol
The human T-cell leukemia/lymphoma virus type 1 (HTLV-1) p30 protein, essential for virus
infectivity in vivo, is required for efficient infection of human dendritic cells (DCs) but not B …

[HTML][HTML] The impact of immune response on HTLV-I in HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP)

H Rafatpanah, RF Hosseini… - Iranian Journal of Basic …, 2013 - ncbi.nlm.nih.gov
Human T lymphotropic virus type I (HTLV-I) is a retrovirus which is associated with adult T
cells leukaemia (ATL) and HTLV-I-associated myelopathy/tropical spastic paraparesis …

Balancing the robustness and predictive performance of biomarkers

P Kirk, A Witkover, CRM Bangham… - Journal of …, 2013 - liebertpub.com
Recent studies have highlighted the importance of assessing the robustness of putative
biomarkers identified from experimental data. This has given rise to the concept of stable …

Repeated Decision Stumping Distils Simple Rules from Single-Cell Data

IA Croydon-Veleslavov, MPH Stumpf - Journal of Computational …, 2024 - liebertpub.com
Single-cell data afford unprecedented insights into molecular processes. But the complexity
and size of these data sets have proved challenging and given rise to a large armory of …

Preapoptotic protease calpain-2 is frequently suppressed in adult T-cell leukemia

M Ishihara, N Araya, T Sato… - Blood, The Journal …, 2013 - ashpublications.org
Adult T-cell leukemia (ATL) is one of the most aggressive hematologic malignancies caused
by human T-lymphotropic virus type 1 (HTLV-1) infection. The prognosis of ATL is extremely …

Soluble IL‐2 receptor and beta‐2 microglobulin as possible serologic markers of neurologic disease in HTLV‐1 infection

C Toledo‐Cornell, S Santos, G Orge… - Journal of medical …, 2014 - Wiley Online Library
The human T‐cell leukemia virus (HTLV‐1) is the causative agent of a variety of neurologic
diseases, including HTLV‐1 Associated Myelopathy (HAM/TSP) and overactive bladder …