[HTML][HTML] Epigenetic regulation in metabolic diseases: mechanisms and advances in clinical study

YL Wu, ZJ Lin, CC Li, X Lin, SK Shan, B Guo… - … and Targeted Therapy, 2023 - nature.com
Epigenetics regulates gene expression and has been confirmed to play a critical role in a
variety of metabolic diseases, such as diabetes, obesity, non-alcoholic fatty liver disease …

[HTML][HTML] Stress, epigenetics, and aging: unraveling the intricate crosstalk

Z Wu, J Qu, W Zhang, GH Liu - Molecular Cell, 2024 - cell.com
Aging, as a complex process involving multiple cellular and molecular pathways, is known to
be exacerbated by various stresses. Because responses to these stresses, such as oxidative …

Recent trends in cancer therapy: A review on the current state of gene delivery

EB Yahya, AM Alqadhi - Life Sciences, 2021 - Elsevier
Cancer treatment has been always considered one of the most critical and vital themes of
clinical issues. Many approaches have been developed, depending on the type and the …

miRNAs orchestration of adrenocortical carcinoma-Particular emphasis on diagnosis, progression and drug resistance

WA El-Dakroury, HM Midan, AI Abulsoud… - … -Research and Practice, 2023 - Elsevier
Adrenocortical carcinoma (ACC) is an uncommon aggressive endocrine malignancy that is
nonetheless associated with significant mortality and morbidity rates because of endocrine …

[HTML][HTML] Roles of microRNAs in abiotic stress response and characteristics regulation of plant

F Zhang, J Yang, N Zhang, J Wu, H Si - Frontiers in Plant Science, 2022 - frontiersin.org
MicroRNAs (miRNAs) are a class of non-coding endogenous small RNAs (long 20–24
nucleotides) that negatively regulate eukaryotes gene expression at post-transcriptional …

[HTML][HTML] Systems and synthetic microRNA biology: from biogenesis to disease pathogenesis

H Matsuyama, HI Suzuki - International journal of molecular sciences, 2019 - mdpi.com
MicroRNAs (miRNAs) are approximately 22-nucleotide-long, small non-coding RNAs that
post-transcriptionally regulate gene expression. The biogenesis of miRNAs involves multiple …

miRNAs driving diagnosis, prognosis and progression in Merkel cell carcinoma

TM Al-Noshokaty, MS Elballal, GK Helal… - … -Research and Practice, 2023 - Elsevier
Merkel cell carcinoma (MCC) is a rare, aggressive form of skin malignancy with a high
recurrence commonly within two to three years of initial diagnosis. The incidence of MCC …

[HTML][HTML] Signaling pathways governing breast cancer stem cells behavior

K Song, M Farzaneh - Stem Cell Research & Therapy, 2021 - Springer
Breast cancer is the second common cancer and the leading cause of malignancy among
females overall. Breast cancer stem cells (BCSCs) are a small population of breast cancer …

[HTML][HTML] Regulatory mechanisms of epigenetic miRNA relationships in human cancer and potential as therapeutic targets

KMT Arif, EK Elliott, LM Haupt, LR Griffiths - Cancers, 2020 - mdpi.com
Simple Summary By the virtue of targeting multiple genes, a microRNA (miRNA) can infer
variable consequences on tumorigenesis by appearing as both a tumour suppressor and …

[HTML][HTML] Histone modifications and non-coding RNAs: mutual epigenetic regulation and role in pathogenesis

IV Bure, MV Nemtsova, EB Kuznetsova - International Journal of …, 2022 - mdpi.com
In the last few years, more and more scientists have suggested and confirmed that
epigenetic regulators are tightly connected and form a comprehensive network of regulatory …