[HTML][HTML] Active fluid de-resuscitation in critically ill patients with septic shock: A systematic review and meta-analysis

AS Messmer, T Dill, M Müller… - European journal of …, 2023 - Elsevier
Purpose To evaluate the impact of active fluid de-resuscitation on mortality in critically ill
patients with septic shock. Methods A systematic search was performed on PubMed …

Improving mixed-integer temporal modeling by generating synthetic data using conditional generative adversarial networks: A case study of fluid overload prediction …

A Rafiei, MG Rad, A Sikora, R Kamaleswaran - Computers in Biology and …, 2024 - Elsevier
Objective The challenge of mixed-integer temporal data, which is particularly prominent for
medication use in the critically ill, limits the performance of predictive models. The purpose …

The application of artificial intelligence in the management of sepsis

J Yang, S Hao, J Huang, T Chen, R Liu, P Zhang… - Medical …, 2023 - degruyter.com
Sepsis is a complex and heterogeneous syndrome that remains a serious challenge to
healthcare worldwide. Patients afflicted by severe sepsis or septic shock are customarily …

Pharmacophenotype identification of intensive care unit medications using unsupervised cluster analysis of the ICURx common data model

A Sikora, A Rafiei, MG Rad, K Keats, SE Smith… - Critical Care, 2023 - Springer
Background Identifying patterns within ICU medication regimens may help artificial
intelligence algorithms to better predict patient outcomes; however, machine learning …

Cluster analysis driven by unsupervised latent feature learning of medications to identify novel pharmacophenotypes of critically ill patients

A Sikora, H Jeong, M Yu, X Chen, B Murray… - Scientific Reports, 2023 - nature.com
Unsupervised clustering of intensive care unit (ICU) medications may identify unique
medication clusters (ie, pharmacophenotypes) in critically ill adults. We performed an …

Machine learning vs. traditional regression analysis for fluid overload prediction in the ICU

A Sikora, T Zhang, DJ Murphy, SE Smith, B Murray… - Scientific Reports, 2023 - nature.com
Fluid overload, while common in the ICU and associated with serious sequelae, is hard to
predict and may be influenced by ICU medication use. Machine learning (ML) approaches …

Fluid overload and mortality in critically ill patients with severe heart failure and cardiogenic shock–An observational cohort study

J Waskowski, MC Michel, R Steffen, AS Messmer… - Frontiers in …, 2022 - frontiersin.org
Objective Patients with heart failure (HF) and cardiogenic shock are especially prone to the
negative effects of fluid overload (FO); however, fluid resuscitation in respective patients is …

Improving irregular temporal modeling by integrating synthetic data to the electronic medical record using conditional GANs: a case study of fluid overload prediction …

A Rafiei, MG Rad, A Sikora, R Kamaleswaran - medRxiv, 2023 - medrxiv.org
Objective The challenge of irregular temporal data, which is particularly prominent for
medication use in the critically ill, limits the performance of predictive models. The purpose …

Using machine-learning to assess the prognostic value of early enteral feeding intolerance in critically ill patients: a retrospective study

O Raphaeli, L Statlender, C Hajaj, I Bendavid… - Nutrients, 2023 - mdpi.com
Background: The association between gastrointestinal intolerance during early enteral
nutrition (EN) and adverse clinical outcomes in critically ill patients is controversial. We …

Influence of fluid accumulation on major adverse kidney events in critically ill patients–an observational cohort study

DM Hofer, L Ruzzante, J Waskowski, AS Messmer… - Annals of intensive …, 2024 - Springer
Background Fluid accumulation (FA) is known to be associated with acute kidney injury
(AKI) during intensive care unit (ICU) stay but data on mid-term renal outcome is scarce. The …