Overview of the 2022 WHO classification of thyroid neoplasms

ZW Baloch, SL Asa, JA Barletta, RA Ghossein… - Endocrine …, 2022 - Springer
This review summarizes the changes in the 5th edition of the WHO Classification of
Endocrine and Neuroendocrine Tumors that relate to the thyroid gland. The new …

[HTML][HTML] Molecular testing for thyroid nodules: the experience at McGill University teaching hospitals in Canada

M Rajab, RJ Payne, VI Forest, M Pusztaszeri - Cancers, 2022 - mdpi.com
Simple Summary The aim of this review is to provide a general overview about the
molecular markers (mutations and alterations) of thyroid cancers, present several molecular …

[HTML][HTML] Molecular features of aggressive thyroid cancer

G Elia, A Patrizio, F Ragusa, SR Paparo… - Frontiers in …, 2022 - frontiersin.org
Poorly differentiated thyroid cancer (PDTC) and anaplastic thyroid cancer (ATC) have a
worse prognosis with respect to well differentiated TC, and the loss of the capability of up …

Thyroid hormone system disrupting chemicals

J Köhrle, C Frädrich - Best Practice & Research clinical endocrinology & …, 2021 - Elsevier
The thyroid hormone system is a main target of endocrine disruptor compounds (EDC) at all
levels of its intricately fine-tuned feedback regulation, synthesis, distribution, metabolism and …

The Italian Consensus for the Classification and Reporting of Thyroid Cytology: Cytohistologic and molecular correlations on 37,371 nodules from a single …

L Torregrossa, AM Poma, E Macerola… - Cancer …, 2022 - Wiley Online Library
Background The Italian Consensus for the Classification and Reporting of Thyroid Cytology
(ICCRTC) includes six diagnostic categories (TIR 1/1C, TIR 2, TIR 3A, TIR 3B, TIR 4, and TIR …

[HTML][HTML] Indeterminate thyroid nodules: from cytology to molecular testing

P Vignali, E Macerola, AM Poma, R Sparavelli… - Diagnostics, 2023 - mdpi.com
Thyroid cancer is the most common malignancy of the endocrine system. Fine-needle
aspiration (FNA) biopsy of thyroid nodules has become the gold standard procedure, in …

The Presence of Typical “BRAFV600E-Like” Atypia in Papillary Thyroid Carcinoma is Highly Specific for the Presence of the BRAFV600E Mutation

J Turchini, L Sioson, A Clarkson, A Sheen… - Endocrine …, 2023 - Springer
Papillary thyroid carcinomas (PTCs) are driven by a variety of molecular abnormalities
including BRAF, RAS, ALK, RET, and NTRK alterations. PTCs driven by the BRAFV600E …

[HTML][HTML] The Impact of BRAF V600E Mutation Allele Frequency on the Histopathological Characteristics of Thyroid Cancer

M Abdulhaleem, S Bandargal, MP Pusztaszeri… - Cancers, 2023 - mdpi.com
Simple Summary This study aimed to investigate the relationship between the allele
frequency (AF) of the BRAF V600E mutation and the histopathological features of papillary …

[HTML][HTML] Characteristics of PTEN Mutation in Thyroid Tumours: A Retrospective Chart Review

S Bandargal, M Rajab, VI Forest, MP Pusztaszeri… - Cancers, 2023 - mdpi.com
Simple Summary PTEN mutation is an extremely rare mutation in thyroid nodules with no
clear prognostic indicators. In this multicenter study of 16 PTEN-mutated thyroid nodules, we …

[HTML][HTML] Role of ST6GAL1 in Thyroid Cancers: Insights from Tissue Analysis and Genomic Datasets

I Gunjača, B Benzon, N Pleić, M Babić Leko… - International Journal of …, 2023 - mdpi.com
Thyroid cancer is the predominant endocrine-related malignancy. ST6 β-galactoside α2, 6-
sialyltransferase 1 (ST6GAL1) has been studied in various types of cancers; however, the …