The multifaceted nature of antimicrobial peptides: Current synthetic chemistry approaches and future directions
BH Gan, J Gaynord, SM Rowe, T Deingruber… - Chemical Society …, 2021 - pubs.rsc.org
Bacterial infections caused by 'superbugs' are increasing globally, and conventional
antibiotics are becoming less effective against these bacteria, such that we risk entering a …
antibiotics are becoming less effective against these bacteria, such that we risk entering a …
Antimicrobial host defence peptides: functions and clinical potential
Cationic host defence peptides (CHDP), also known as antimicrobial peptides, are naturally
occurring peptides that can combat infections through their direct microbicidal properties …
occurring peptides that can combat infections through their direct microbicidal properties …
[HTML][HTML] Strategies to improve bioactive and antibacterial properties of polyetheretherketone (PEEK) for use as orthopedic implants
Z Zheng, P Liu, X Zhang, X Zou, X Mei, S Zhang… - Materials Today Bio, 2022 - Elsevier
Polyetheretherketone (PEEK) has gradually become the mainstream material for preparing
orthopedic implants due to its similar elastic modulus to human bone, high strength …
orthopedic implants due to its similar elastic modulus to human bone, high strength …
Antimicrobial peptides and their therapeutic potential for bacterial skin infections and wounds
A Pfalzgraff, K Brandenburg, G Weindl - Frontiers in pharmacology, 2018 - frontiersin.org
Alarming data about increasing resistance to conventional antibiotics are reported, while at
the same time the development of new antibiotics is stagnating. Skin and soft tissue …
the same time the development of new antibiotics is stagnating. Skin and soft tissue …
Combating implant infections: shifting focus from bacteria to host
S Amin Yavari, SM Castenmiller… - Advanced …, 2020 - Wiley Online Library
The widespread use of biomaterials to support or replace body parts is increasingly
threatened by the risk of implant‐associated infections. In the quest for finding novel anti …
threatened by the risk of implant‐associated infections. In the quest for finding novel anti …
[HTML][HTML] Reassessing the host defense peptide landscape
Current research has demonstrated that small cationic amphipathic peptides have strong
potential not only as antimicrobials, but also as antibiofilm agents, immune modulators, and …
potential not only as antimicrobials, but also as antibiofilm agents, immune modulators, and …
The immunology of host defence peptides: beyond antimicrobial activity
Host defence peptides (HDPs) are short, cationic amphipathic peptides with diverse
sequences that are produced by various cells and tissues in all complex life forms. HDPs …
sequences that are produced by various cells and tissues in all complex life forms. HDPs …
Antimicrobial peptides–Advances in development of therapeutic applications
The severe infection is becoming a significant health problem which threaten the lives of
patients and the safety and economy of society. In the way of finding new strategy …
patients and the safety and economy of society. In the way of finding new strategy …
Alternatives to antibiotics—a pipeline portfolio review
L Czaplewski, R Bax, M Clokie, M Dawson… - The Lancet infectious …, 2016 - thelancet.com
Antibiotics have saved countless lives and enabled the development of modern medicine
over the past 70 years. However, it is clear that the success of antibiotics might only have …
over the past 70 years. However, it is clear that the success of antibiotics might only have …
Alternatives to conventional antibiotics in the era of antimicrobial resistance
As more antibiotics are rendered ineffective by drug-resistant bacteria, focus must be shifted
towards alternative therapies for treating infections. Although several alternatives already …
towards alternative therapies for treating infections. Although several alternatives already …