Transfusion-related acute lung injury (TRALI) is a severe adverse event and a leading cause
of transfusion-associated death. Its poor associated prognosis is due, in large part, to the …

Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are serious lung
injuries caused by various factors, leading to increased permeability of the alveolar-capillary …

Recent studies of severe acute inflammatory lung disease including COVID-19 identify
macrophages to drive pulmonary hyperinflammation and long-term damage such as fibrosis …

Introduction Acute lung injury (ALI) is a lung disease characterized by inflammation and still
requires further drug development. Forsythiaside A as the active compound of Forsythiae …

Neutrophil extracellular traps (NETs) are involved in the activation and dysfunction of
multiple overlapping and interacting pathways, including the immune response to injury …

Background: This document updates previously published Clinical Practice Guidelines for
the management of patients with acute respiratory distress syndrome (ARDS), incorporating …

The pathobiology of respiratory failure in COVID-19 consists of a complex interplay between
viral cytopathic effects and a dysregulated host immune response. In critically ill patients …

Purpose A hallmark of acute respiratory distress syndrome (ARDS) is hypoxaemic
respiratory failure due to pulmonary vascular hyperpermeability. The tyrosine kinase …

Acute respiratory distress syndrome (ARDS) is a rapidly progressive form of respiratory
failure that accounts for 10% of admissions to the ICU and is associated with approximately …

Background Neutrophil extracellular traps (NETs) can cause acute lung injury (ALI)/acute
respiratory distress syndrome (ARDS) by inducing macrophage pyroptosis. The purpose of …