Although it has been suggested that toll-like receptor (TLR) 3 and TLR4 activation alters
mesenchymal stromal cells (MSCs)'immunoregulatory function as anti-or pro-inflammatory …

Background Necroptosis of macrophages is a necessary element in reinforcing
intrapulmonary inflammation during acute lung injury (ALI). However, the molecular …

Acute respiratory distress syndrome (ARDS) is a major cause of hypoxemic respiratory
failure in adults, leading to the requirement for mechanical ventilation and poorer outcomes …

Introduction Patients with COVID-19-related acute respiratory distress syndrome (ARDS)
show limited systemic hyperinflammation, but immunomodulatory treatments are effective …

Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are serious lung
injuries caused by various factors, leading to increased permeability of the alveolar-capillary …

Sepsis, defined as the life-threatening dysregulated host response to an infection leading to
organ dysfunction, is considered as one of the leading causes of mortality worldwide …

Aims To investigate the role and mechanisms of methyltransferase-like 3 (METTL3) in the
pathogenesis of lipopolysaccharide (LPS)-induced acute lung injury (ALI). Main methods …

Background Neutrophil extracellular traps (NETs) can cause acute lung injury (ALI)/acute
respiratory distress syndrome (ARDS) by inducing macrophage pyroptosis. The purpose of …

Acute respiratory distress syndrome (ARDS) is responsible for 400,000 deaths annually
worldwide. Few improvements have been made despite five decades of research, partially …

Pulmonary inflammation is one of the most reported tissue inflammations in clinic.
Successful suppression of inflammation is vital to prevent further inevitably fatal lung …