Background Alveolar hypercoagulation and fibrinolytic inhibition play a central role in
refractory hypoxemia in acute respiratory distress syndrome (ARDS), but it lacks effective …

Acute respiratory distress syndrome (ARDS) has had no mortality-improving
pharmacological intervention despite 50 years of high-caliber research due to its …

Abstract Objective Alveolar type II (ATII) cells produce pulmonary surfactant (PS) essential
for maintaining lung function. The aberration or depletion of PS can cause alveolar collapse …

Background Acute Respiratory Distress Syndrome (ARDS) or its earlier stage Acute lung
injury (ALI), is a worldwide health concern that jeopardizes human well-being. Currently, the …

Despite significant progress in our understanding of the pathophysiology of sepsis and
extensive clinical research, there are few proven therapies addressing the underlying …

Purpose The purpose of this study is to address the high mortality and poor prognosis
associated with Acute Respiratory Distress Syndrome (ARDS), conditions characterized by …

Acute respiratory distress syndrome (ARDS) is a highly heterogeneous clinical condition.
Shock is a poor prognostic sign in ARDS, and heterogeneity in its pathophysiology may be a …

Acute lung injury (ALI) is the pathophysiological precursor of acute respiratory distress
syndrome. It is characterized by increased oxidative stress and exaggerated inflammatory …

Extracellular vesicles mediate intercellular communication by transporting biologically active
macromolecules. Our prior studies have demonstrated that the nuclear factor of activated T …

Acute lung injury (ALI) is a common and critical respiratory disorder caused by various
factors, with viral infection being the leading contributor. Dehydroandrographolide (DAP), a …