[HTML][HTML] Microarray analysis identifies lncFirre as a potential regulator of obesity-related acute lung injury
W Tang, S Wu, Y Tang, J Ma, Y Ao, L Liu, K Wei - Life Sciences, 2024 - Elsevier
Aims The inflammatory response in acute lung injury/acute respiratory distress syndrome
(ALI/ARDS) is heightened in obesity. The aim of this study was to investigate whether …
(ALI/ARDS) is heightened in obesity. The aim of this study was to investigate whether …
[HTML][HTML] S1PR3 inhibition protects against LPS-induced ARDS by inhibiting NF-κB and improving mitochondrial oxidative phosphorylation
J Peng, R Tang, J He, Q Yu, D Wang… - Journal of Translational …, 2024 - ncbi.nlm.nih.gov
Background Inflammation and endothelial barrier dysfunction are the major
pathophysiological changes in acute respiratory distress syndrome (ARDS). Sphingosine-1 …
pathophysiological changes in acute respiratory distress syndrome (ARDS). Sphingosine-1 …
Host-targeted approaches to sepsis due to community-acquired pneumonia
C Cilloniz, A Torres - EBioMedicine, 2022 - thelancet.com
Sepsis, a life-threatening condition, is the main complication of severe community-acquired
pneumonia (CAP) observed in approximately one in three patients with severe CAP. 1 The …
pneumonia (CAP) observed in approximately one in three patients with severe CAP. 1 The …
[HTML][HTML] Biomarker Analysis Provides Evidence for Host Response Homogeneity in Patients With COVID-19
RBE van Amstel, EHA Michels, B Appelman… - CHEST Critical …, 2024 - Elsevier
Background The exploration of subphenotypes in hospitalized patients with COVID-19 has
garnered substantial attention. Most existing studies operate under the assumption of …
garnered substantial attention. Most existing studies operate under the assumption of …
MSCs interaction with the host lung microenvironment: An overlooked aspect?
DJ Weiss, S Rolandsson Enes - Frontiers in Immunology, 2022 - frontiersin.org
Mesenchymal stromal cells (MSCs) were identified more than 50 years ago, and research
advances have promoted the translation of pre-clinical studies into clinical settings in …
advances have promoted the translation of pre-clinical studies into clinical settings in …
[HTML][HTML] Hydrogen alleviates impaired lung epithelial barrier in acute respiratory distress syndrome via inhibiting Drp1-mediated mitochondrial fission through the Trx1 …
Y Long, Y Ang, W Chen, Y Wang, M Shi, F Hu… - Free Radical Biology …, 2024 - Elsevier
Acute respiratory distress syndrome (ARDS) is an acute and severe clinical complication
lacking effective therapeutic interventions. The disruption of the lung epithelial barrier plays …
lacking effective therapeutic interventions. The disruption of the lung epithelial barrier plays …
Clustering COVID-19 ARDS patients through the first days of ICU admission. An analysis of the CIBERESUCICOVID Cohort
Background Acute respiratory distress syndrome (ARDS) can be classified into sub-
phenotypes according to different inflammatory/clinical status. Prognostic enrichment was …
phenotypes according to different inflammatory/clinical status. Prognostic enrichment was …
[HTML][HTML] Lactobacillus reuteri Ameliorates Lipopolysaccharide-Induced Acute Lung Injury by Modulating the Gut Microbiota in Mice
J Shen, S Wang, Y Huang, Z Wu, S Han, H Xia, H Chen… - Nutrients, 2023 - mdpi.com
Acute lung injury (ALI) causes lung inflammation and edema as well as resulting in gut
microbiota disorder. Probiotics, however, can improve the gut microbiota composition and …
microbiota disorder. Probiotics, however, can improve the gut microbiota composition and …
Interplay between pulmonary epithelial stem cells and innate immune cells contribute to the repair and regeneration of ALI/ARDS
J Wang, X Peng, N Yuan, B Wang, S Chen… - Translational …, 2024 - Elsevier
Mammalian lung is the important organ for ventilation and exchange of air and blood. Fresh
air and venous blood are constantly delivered through the airway and vascular tree to the …
air and venous blood are constantly delivered through the airway and vascular tree to the …
A combination of mild-moderate hypoxemia and low compliance is highly prevalent in persistent ARDS: a retrospective study
E Papoutsi, I Andrianopoulos, V Mavrikaki, M Bolaki… - Respiratory …, 2024 - Springer
Abstract Background The Acute Respiratory Distress Syndrome (ARDS) is characterized by
lung inflammation and edema, impairing both oxygenation and lung compliance. Recent …
lung inflammation and edema, impairing both oxygenation and lung compliance. Recent …