[HTML][HTML] Resveratrol influences pulmonary mechanics and inflammatory response in a porcine ARDS model

R Rissel, L Kirchner, M Renz, K Mohnke, J Riedel… - Life Sciences, 2023 - Elsevier
Aims Influencing the inflammatory response represents an important branch in ARDS
research. The naturally occurring polyphenol derivative resveratrol has already been …

Rationally designed an innovative proximity labeling near-infrared fluorogenic probe for imaging of peroxynitrite in acute lung injury

D Tang, N Xu, Y Fu, W Peng, J Wu, H Liu, F Yu - Chinese Chemical Letters, 2024 - Elsevier
Acute lung injury (ALI) is a serious clinical condition with a high mortality rate. Oxidative
stress and inflammatory responses play pivotal roles in the pathogenesis of ALI. ONOO− is a …

Smoking on the risk of acute respiratory distress syndrome: a systematic review and meta-analysis

L Zhang, J Xu, Y Li, F Meng, W Wang - Critical Care, 2024 - Springer
Background The relationship between smoking and the risk of acute respiratory distress
syndrome (ARDS) has been recognized, but the conclusions have been inconsistent. This …

Th17/Treg balance: the bloom and wane in the pathophysiology of sepsis

X Liu, L Chen, W Peng, H Deng, H Ni, H Tong… - Frontiers in …, 2024 - frontiersin.org
Sepsis is a multi-organ dysfunction characterized by an unregulated host response to
infection. It is associated with high morbidity, rapid disease progression, and high mortality …

Shenfu injection targets the PI3K-AKT pathway to regulate autophagy and apoptosis in acute respiratory distress syndrome caused by sepsis

J Chen, W Ding, Z Zhang, Q Li, M Wang, J Feng… - Phytomedicine, 2024 - Elsevier
Background Sepsis is a life-threatening organ dysfunction caused by an exaggerated
response to infection. In the lungs, one of the most susceptible organs, this can manifest as …

TM9SF1 offers utility as an efficient predictor of clinical severity and mortality among acute respiratory distress syndrome patients

F Cao, L Zhang, Z Zhao, X Shen, J Xiong… - Frontiers in …, 2024 - frontiersin.org
Introduction Acute respiratory distress syndrome (ARDS) is a major cause of death among
critically ill patients in intensive care settings, underscoring the need to identify biomarkers …

[HTML][HTML] GTS-21 attenuates ACE/ACE2 ratio and glycocalyx shedding in lipopolysaccharide-induced acute lung injury by targeting macrophage polarization derived …

W Zhu, F Wang, C Hu, Q Zhao, D Zhang… - International …, 2024 - Elsevier
Acute lung injury (ALI) has received considerable attention in intensive care owing to its high
mortality rate. It has been demonstrated that the selective alpha7 nicotinic acetylcholine …

[HTML][HTML] Cell Proliferation and Apoptosis—Key Players in the Lung Aging Process

J Ancer-Rodríguez, Y Gopar-Cuevas… - International Journal of …, 2024 - mdpi.com
Currently, the global lifespan has increased, resulting in a higher proportion of the
population over 65 years. Changes that occur in the lung during aging increase the risk of …

Synergistic Pulmonoprotective Effect of Natural Prolyl Oligopeptidase Inhibitors in In Vitro and In Vivo Models of Acute Respiratory Distress Syndrome

S Zerikiotis, P Efentakis, D Dapola, A Agapaki… - International Journal of …, 2023 - mdpi.com
Acute respiratory distress syndrome (ARDS) is a highly morbid inflammatory lung disease
with limited pharmacological interventions. The present study aims to evaluate and compare …

Advances and Applications of Lung Organoids in the Research on Acute Respiratory Distress Syndrome (ARDS)

X Zhang, L Su, P Pan - Journal of Clinical Medicine, 2024 - mdpi.com
Acute Respiratory Distress Syndrome (ARDS) is a sudden onset of lung injury characterized
by bilateral pulmonary edema, diffuse inflammation, hypoxemia, and a low P/F ratio …