This review examines the merits of 'food addiction'as an explanation of excessive eating (ie,
eating in excess of what is required to maintain a healthy body weight). It describes various …

Based on their pharmacological properties, psychoactive drugs are supposed to take control
of the natural reward system to finally drive compulsory drug seeking and consumption …

Drug addiction is a neuropsychiatric disorder with grave personal consequences that has an
extraordinary global economic impact. Despite decades of research, the options available to …

Poorly regulated reward seeking is a central feature of substance use disorder. Recent
research shows that rewarding drug-related experiences induce synchronous activation of a …

Since its rediscovery at the beginning of the 21st Century, memory reconsolidation has been
proposed to be a therapeutic target for reducing the impact of emotional memories that can …

Since the first experimental hint for the existence of “an actual desire or striving for the drug”
in nonhuman animals by Sidney Spragg in the late 1930s, much effort has been expended …

Cocaine is known to increase brain dopamine at supranormal levels in comparison to
alternative nondrug rewards. According to the dopamine hypothesis of addiction, this …

The idea that interconnected neuronal ensembles code for specific behaviors has been
around for decades; however, recent technical improvements allow studying these networks …

In abstinent drug addicts, cues formerly associated with drug-taking experiences gain
relapse-inducing potency ('incubate') over time. Animal models of incubation may help …

To test the hypothesis that drugs of abuse and their conditioned stimuli (CSs) enhance
memory consolidation, the effects of post-training exposure to cocaine and nicotine were …