Analysis of CUGBP1 targets identifies GU-repeat sequences that mediate rapid mRNA decay
B Rattenbacher, D Beisang, DL Wiesner… - … and cellular biology, 2010 - Taylor & Francis
CUG-repeat binding protein 1 (CUGBP1) mediates selective mRNA decay by binding to GU-
rich elements (GREs) containing the sequence UGUUUGUUUGU found in the 3 …
rich elements (GREs) containing the sequence UGUUUGUUUGU found in the 3 …
KSHV inhibits stress granule formation by viral ORF57 blocking PKR activation
NR Sharma, V Majerciak, MJ Kruhlak… - PLoS …, 2017 - journals.plos.org
TIA-1 positive stress granules (SG) represent the storage sites of stalled mRNAs and are
often associated with the cellular antiviral response. In this report, we provide evidence that …
often associated with the cellular antiviral response. In this report, we provide evidence that …
Systematic analysis of posttranscriptional gene expression
AR Morris, N Mukherjee… - … Reviews: Systems Biology …, 2010 - Wiley Online Library
Recent systems studies of gene expression have begun to dissect the layers of regulation
that underlie the eukaryotic transcriptome, the combined consequence of transcriptional and …
that underlie the eukaryotic transcriptome, the combined consequence of transcriptional and …
[HTML][HTML] RNA recognition and stress granule formation by TIA proteins
Stress granule (SG) formation is a primary mechanism through which gene expression is
rapidly modulated when the eukaryotic cell undergoes cellular stresses (including heat …
rapidly modulated when the eukaryotic cell undergoes cellular stresses (including heat …
Structure, dynamics and RNA binding of the multi-domain splicing factor TIA-1
I Wang, J Hennig, PKA Jagtap, M Sonntag… - Nucleic acids …, 2014 - academic.oup.com
Alternative pre-messenger ribonucleic acid (pre-mRNA) splicing is an essential process in
eukaryotic gene regulation. The T-cell intracellular antigen-1 (TIA-1) is an apoptosis …
eukaryotic gene regulation. The T-cell intracellular antigen-1 (TIA-1) is an apoptosis …
Post-transcriptional gene regulation by HuR promotes a more tumorigenic phenotype
K Mazan-Mamczarz, PR Hagner, S Corl, S Srikantan… - Oncogene, 2008 - nature.com
In a breast tumor xenograft model, the MCT-1 oncogene increases the in vivo tumorgenicity
of MCF7 cells by promoting angiogenesis and inhibiting apoptosis. Increases in the tumor …
of MCF7 cells by promoting angiogenesis and inhibiting apoptosis. Increases in the tumor …
[HTML][HTML] Post-transcriptional control of the hypoxic response by RNA-binding proteins and microRNAs
Mammalian gene expression patterns change profoundly in response to low oxygen levels.
These changes in gene expression programs are strongly influenced by post-transcriptional …
These changes in gene expression programs are strongly influenced by post-transcriptional …
NF90 selectively represses the translation of target mRNAs bearing an AU-rich signature motif
Y Kuwano, R Pullmann Jr, BS Marasa… - Nucleic acids …, 2010 - academic.oup.com
The RNA-binding protein nuclear factor 90 (NF90) has been implicated in the stabilization,
transport and translational control of several target mRNAs. However, a systematic analysis …
transport and translational control of several target mRNAs. However, a systematic analysis …
Low expression of novel lncRNA RP11-462C24. 1 suggests a biomarker of poor prognosis in colorectal cancer
D Shi, H Zheng, C Zhuo, J Peng, D Li, Y Xu, X Li… - Medical oncology, 2014 - Springer
Long noncoding RNAs (lncRNAs) have recently emerged as a major class of regulatory
molecules, which were involved in a broad range of biological processes and complex …
molecules, which were involved in a broad range of biological processes and complex …
Control of messenger RNA fate by RNA‐binding proteins: an emphasis on mammalian spermatogenesis
Posttranscriptional status of messenger RNAs (mRNA) can be affected by many factors,
most of which are RNA‐binding proteins (RBP) that either bind mRNA in a nonspecific …
most of which are RNA‐binding proteins (RBP) that either bind mRNA in a nonspecific …