The RNA-binding protein TIAR is an mRNA-binding protein that acts as a translational
repressor, particularly important under conditions of cellular stress. It binds to target mRNA …

Abstract TIA-1 (T-cell restricted intracellular antigen-1) is an RNA-binding protein involved in
splicing and translational repression. It mainly interacts with RNA via its second and third …

Simple Summary T-cell intracellular antigen 1 (TIA1/TIA-1) and its paralog TIA1-related/like
protein (TIAL1/TIAR) have been implicated in the regulation and/or modulation of gene …

Welander distal myopathy (WDM) is a muscle dystrophy characterized by adult-onset distal
muscle weakness, prevalently impacting the distal long extensors of the hands and feet …

T-cell intracellular antigen-1 (TIA-1) is a key DNA/RNA binding protein that regulates
translation by sequestering target mRNAs in stress granules (SG) in response to stress …

Background TIA-1-related (TIAR) protein is a shuttling RNA-binding protein involved in
several steps of RNA metabolism. While in the nucleus TIAR participates to alternative …

In Caenorhabditis elegans, physiological germ cell apoptosis eliminates more than half of
the cells in the hermaphrodite gonad to support gamete quality and germline homeostasis …

Control of gene expression depends on genetics and environmental factors. The T-cell
intracellular antigens T-cell intracellular antigen 1 (TIA1), TIA1-like/related protein …

T-cell intracellular antigen-1 (TIA-1) plays a pleiotropic role in cell homeostasis through the
regulation of alternative pre-mRNA splicing and mRNA translation by recognising uridine …

TIA (T-cell intracellular antigens)-knockdown HeLa cells show an increase in ribosomes and
translational machinery components. This increase correlates with specific changes in …