We encounter pathogens on a daily basis and our immune system has evolved to mount an
immune response following an infection. An interesting phenomenon that has evolved in …

The use of live Listeria-based vaccines carries serious difficulties when administrated to
immunocompromised individuals. However, cellular carriers have the advantage of inducing …

Background. The success of many pathogens relies on their ability to circumvent the innate
and adaptive immune defenses. How bacterial pathogens subvert adaptive immune …

Motivation Proteasomal cleavage is a key component in protein turnover, as well as antigen
processing and presentation. Although tools for proteasomal cleavage prediction are …

Delivery of macromolecules into the cytosolic space of eukaryotic cells is a pressing
challenge in biopharmaceutics. Macromolecules are often encapsulated into liposomes for …

LLO is the major immuno-dominant antigen in listeriosis and is also required for protective
immunity. Two forms of LLO can be observed in endosomal membranes, a LLO intact form …

1.1. 1 The importance of class I antigen presentation and adaptive immune response 1 1.1.
2 Antigen presentation in the context of cancer 3 1.1. 3 Metrics of antigen presentation and …

Proteasomal cleavage is a key component in protein turnover, as well as antigen
presentation and subsequent immune response. Herein we present pepsickle, an open …