Update on melatonin receptors: IUPHAR Review 20

R Jockers, P Delagrange… - British journal of …, 2016 - Wiley Online Library
Melatonin receptors are seven transmembrane‐spanning proteins belonging to the GPCR
superfamily. In mammals, two melatonin receptor subtypes exist‐MT1 and MT2‐encoded by …

[HTML][HTML] Melatonin and the ovary: physiological and pathophysiological implications

H Tamura, Y Nakamura, A Korkmaz, LC Manchester… - Fertility and sterility, 2009 - Elsevier
OBJECTIVE: To summarize the role of melatonin in the physiology and pathophysiology of
the ovary. DESIGN: Review of literature. SETTING: University Health Science Center …

Homogeneous and heterogeneous catalysts for multicomponent reactions

MJ Climent, A Corma, S Iborra - RSC advances, 2012 - pubs.rsc.org
Organic synthesis performed through multicomponent reactions is an attractive area of
research in organic chemistry. Multicomponent reactions involve more than two starting …

Melatonin signaling and cell protection function

F Luchetti, B Canonico, M Betti… - The FASEB …, 2010 - Wiley Online Library
Besides its well‐known regulatory role on circadian rhythm, the pineal gland hormone
melatonin has other biological functions and a distinct metabolism in various cell types and …

Melatonin and pregnancy in the human

H Tamura, Y Nakamura, MP Terron, LJ Flores… - Reproductive …, 2008 - Elsevier
The purpose of this systematic review is to access the current state of knowledge concerning
the role for melatonin in human pregnancy. Melatonin is a neuroendocrine hormone …

MT1 and MT2 Melatonin Receptors: Ligands, Models, Oligomers, and Therapeutic Potential

DP Zlotos, R Jockers, E Cecon, S Rivara… - Journal of medicinal …, 2014 - ACS Publications
Numerous physiological functions of the pineal gland hormone melatonin are mediated via
activation of two G-protein-coupled receptors, MT1 and MT2. The melatonergic drugs on the …

Melatonin regulates the activities of ovary and delays the fertility decline in female animals via MT1/AMPK pathway

L Zhang, Z Zhang, J Wang, D Lv, T Zhu… - Journal of pineal …, 2019 - Wiley Online Library
Female fertility irreversibly declines with aging, and this is primarily associated with the
decreased quality and quantity of oocytes. To evaluate whether a long‐term of melatonin …

Melatonin receptors in the eye: location, second messengers and role in ocular physiology

P Alarma-Estrany, J Pintor - Pharmacology & therapeutics, 2007 - Elsevier
The pineal hormone melatonin, an important regulator of circadian and seasonal rhythms,
has a role in ocular pathophysiology. In addition to the pineal gland, melatonin synthesis is …

Beneficial effects of melatonin on in vitro bovine embryonic development are mediated by melatonin receptor 1

F Wang, XZ Tian, L Zhang, C Gao, CJ He… - Journal of pineal …, 2014 - Wiley Online Library
In the current study, a fundamental question, that is, the mechanisms related to the beneficial
effects of melatonin on mammalian embryonic development, was addressed. To examine …

Indole-based melatonin analogues: Synthetic approaches and biological activity

SY Wang, XC Shi, P Laborda - European Journal of Medicinal Chemistry, 2020 - Elsevier
Melatonin is a natural hormone primarily released by the pineal gland that regulates the
sleep-wake cycles. The diverse biological applications of melatonin, together with the need …