Real-time monitoring the interfacial dynamic processes at model cell membranes: Taking cell penetrating peptide TAT as an example
A real-time and molecule-level monitoring of the interfacial dynamic interactions between
molecules and a cell membrane is of vital importance. Herein, taking TAT, one of the most …
molecules and a cell membrane is of vital importance. Herein, taking TAT, one of the most …
Biophysical characterization of LTX-315 anticancer peptide interactions with model membrane platforms: effect of membrane surface charge
LTX-315 is a clinical-stage, anticancer peptide therapeutic that disrupts cancer cell
membranes. Existing mechanistic knowledge about LTX-315 has been obtained from cell …
membranes. Existing mechanistic knowledge about LTX-315 has been obtained from cell …
Free energy barrier for melittin reorientation from a membrane-bound state to a transmembrane state
SJ Irudayam, T Pobandt… - The Journal of Physical …, 2013 - ACS Publications
An important step in a phospholipid membrane pore formation by melittin antimicrobial
peptide is a reorientation of the peptide from a surface into a transmembrane conformation …
peptide is a reorientation of the peptide from a surface into a transmembrane conformation …
Individual roles of peptides PGLa and Magainin 2 in synergistic membrane poration
Synergy between antimicrobial peptides PGLa and Magainin 2 (MAG2) provides an efficient
way to enhance their antimicrobial ability. However, the underlying molecular mechanism of …
way to enhance their antimicrobial ability. However, the underlying molecular mechanism of …
Interactions of aqueous imidazolium-based ionic liquid mixtures with solid-supported phospholipid vesicles
P Losada-Perez, M Khorshid, FU Renner - PLoS One, 2016 - journals.plos.org
Despite the environmentally friendly reputation of ionic liquids (ILs), their safety has been
recently questioned given their potential as cytotoxic agents. The fundamental mechanisms …
recently questioned given their potential as cytotoxic agents. The fundamental mechanisms …
Self-association of antimicrobial peptides: A molecular dynamics simulation study on bombinin
Antimicrobial peptides (AMPs) are a diverse group of membrane-active peptides which play
a crucial role as mediators of the primary host defense against microbial invasion. Many …
a crucial role as mediators of the primary host defense against microbial invasion. Many …
[PDF][PDF] Mechanism of anticancer effects of antimicrobial peptides
Abstract Antimicrobial Peptides (AMPs) were first known as a group of innate immune
products that mainly targets on the invading pathogens among multiple species. The …
products that mainly targets on the invading pathogens among multiple species. The …
Asymmetric disturbance and permeabilization of bilayer membranes by 3-nm carbon dots
Small-sized fluorescent carbon dots (CDs) are gaining increasing attention in the field of
biomedical applications. The environmental and biological compatibility of positively …
biomedical applications. The environmental and biological compatibility of positively …
Effect of N-terminal modification on the antimicrobial activity of nisin
X Yu, N Lu, J Wang, Z Chen, C Chen… - Food Control, 2020 - Elsevier
Nisin, the only antimicrobial peptide that has GRAS (generally considered as safe) status
from both WHO and FDA, has the potential to become an important natural antibiotic as …
from both WHO and FDA, has the potential to become an important natural antibiotic as …
Membrane-Active Peptides Attack Cell Membranes in a Lipid-Regulated Curvature-Generating Mode
Z Deng, X You, Z Lin, X Dong, B Yuan… - The Journal of Physical …, 2023 - ACS Publications
Membrane-active peptides (MAPs) exhibit great potential in biomedical applications due to
their unique ability to overcome the cell membrane barrier. However, the interactions …
their unique ability to overcome the cell membrane barrier. However, the interactions …