[HTML][HTML] Vesicle-based artificial cells: materials, construction methods and applications

Y Lu, G Allegri, J Huskens - Materials horizons, 2022 - pubs.rsc.org
The construction of artificial cells with specific cell-mimicking functions helps to explore
complex biological processes and cell functions in natural cell systems and provides an …

[HTML][HTML] Artificial lipid membranes: Past, present, and future

CG Siontorou, GP Nikoleli, DP Nikolelis, SK Karapetis - Membranes, 2017 - mdpi.com
The multifaceted role of biological membranes prompted early the development of artificial
lipid-based models with a primary view of reconstituting the natural functions in vitro so as to …

DNA-based communication in populations of synthetic protocells

A Joesaar, S Yang, B Bögels, A van der Linden… - Nature …, 2019 - nature.com
Developing molecular communication platforms based on orthogonal communication
channels is a crucial step towards engineering artificial multicellular systems. Here, we …

Hierarchical self-assembly of a copolymer-stabilized coacervate protocell

AF Mason, BC Buddingh', DS Williams… - Journal of the …, 2017 - ACS Publications
Complex coacervate microdroplets are finding increased utility in synthetic cell applications
due to their cytomimetic properties. However, their intrinsic membrane-free nature results in …

Synthesis of lipid membranes for artificial cells

KA Podolsky, NK Devaraj - Nature Reviews Chemistry, 2021 - nature.com
A major goal of synthetic biology is to understand the transition between non-living matter
and life. The bottom-up development of an artificial cell would provide a minimal system with …

Two-way chemical communication between artificial and natural cells

R Lentini, NY Martín, M Forlin, L Belmonte… - ACS central …, 2017 - ACS Publications
Artificial cells capable of both sensing and sending chemical messages to bacteria have yet
to be built. Here we show that artificial cells that are able to sense and synthesize quorum …

Reconstituting natural cell elements in synthetic cells

NJ Gaut, KP Adamala - Advanced Biology, 2021 - Wiley Online Library
Building a live cell from non‐living building blocks would be a fundamental breakthrough in
biological sciences, and it would enable engineering new lineages of life, not directly …

Molecular cybernetics: challenges toward cellular chemical artificial intelligence

S Murata, T Toyota, SM Nomura… - Advanced Functional …, 2022 - Wiley Online Library
Research on so‐called “chemical artificial intelligence”(CAI) is an emerging field with the
aim of constructing information‐processing systems with learning capabilities based on …

[HTML][HTML] Synthetic cells with self-activating optogenetic proteins communicate with natural cells

O Adir, MR Albalak, R Abel, LE Weiss, G Chen… - Nature …, 2022 - nature.com
Abstract Development of regulated cellular processes and signaling methods in synthetic
cells is essential for their integration with living materials. Light is an attractive tool to achieve …

Reaction–diffusion patterning of DNA-based artificial cells

A Leathers, M Walczak, RA Brady… - Journal of the …, 2022 - ACS Publications
Biological cells display complex internal architectures with distinct micro environments that
establish the chemical heterogeneity needed to sustain cellular functions. The continued …