Aptamer functionalized nanomaterials for biomedical applications: Recent advances and new horizons

M Mahmoudpour, S Ding, Z Lyu, G Ebrahimi, D Du… - Nano Today, 2021 - Elsevier
With the advancement of functional nanomaterials and aptamer selection technologies,
aptamer functionalized nanomaterials (AFMs) open various methods to design new sensing …

Ligand‐installed nanocarriers toward precision therapy

P Mi, H Cabral, K Kataoka - Advanced Materials, 2020 - Wiley Online Library
Abstract Development of drug‐delivery systems that selectively target neoplastic cells has
been a major goal of nanomedicine. One major strategy for achieving this milestone is to …

Investigating the optimal size of anticancer nanomedicine

L Tang, X Yang, Q Yin, K Cai, H Wang… - Proceedings of the …, 2014 - National Acad Sciences
Nanomedicines (NMs) offer new solutions for cancer diagnosis and therapy. However,
extension of progression-free interval and overall survival time achieved by Food and Drug …

Protease-triggered, spatially controlled DNA assembly in apoptotic cells for early evaluation of therapeutic efficacy

Z Di, X Yi, L Li - Journal of the American Chemical Society, 2023 - ACS Publications
Despite numerous advances in the use of DNA as building blocks to assemble complex
structures, the dearth of strategies that allow for protease-controlled in situ DNA assembly in …

Selective in vivo metabolic cell-labeling-mediated cancer targeting

H Wang, R Wang, K Cai, H He, Y Liu, J Yen… - Nature chemical …, 2017 - nature.com
Distinguishing cancer cells from normal cells through surface receptors is vital for cancer
diagnosis and targeted therapy. Metabolic glycoengineering of unnatural sugars provides a …

Nonporous silica nanoparticles for nanomedicine application

L Tang, J Cheng - Nano today, 2013 - Elsevier
Nanomedicine, the use of nanotechnology for biomedical applications, has potential to
change the landscape of the diagnosis and therapy of many diseases. In the past several …

G-quadruplex oligonucleotide AS1411 as a cancer-targeting agent: Uses and mechanisms

PJ Bates, EM Reyes-Reyes, MT Malik… - … et Biophysica Acta (BBA …, 2017 - Elsevier
Background AS1411 is a 26-mer G-rich DNA oligonucleotide that forms a variety of G-
quadruplex structures. It was identified based on its cancer-selective antiproliferative activity …

Ultrasmall inorganic nanoparticles: State-of-the-art and perspectives for biomedical applications

K Zarschler, L Rocks, N Licciardello, L Boselli… - … , Biology and Medicine, 2016 - Elsevier
Ultrasmall nanoparticulate materials with core sizes in the 1-3 nm range bridge the gap
between single molecules and classical, larger-sized nanomaterials, not only in terms of …

Radiolabeling nanomaterials for multimodality imaging: New insights into nuclear medicine and cancer diagnosis

J Ge, Q Zhang, J Zeng, Z Gu, M Gao - Biomaterials, 2020 - Elsevier
Nuclear medicine imaging has been developed as a powerful diagnostic approach for
cancers by detecting gamma rays directly or indirectly from radionuclides to construct …

[HTML][HTML] Aptamers: active targeting ligands for cancer diagnosis and therapy

X Wu, J Chen, M Wu, JX Zhao - Theranostics, 2015 - ncbi.nlm.nih.gov
Aptamers, including DNA, RNA and peptide aptamers, are a group of promising recognition
units that can specifically bind to target molecules and cells. Due to their excellent specificity …