Introduction: Metastatic breast cancer is one of the most devastating cancers that have no
cure. Many therapeutic and diagnostic strategies have been extensively studied in the past …

Aptamers are high affinity single-stranded DNA/RNA molecules, produced by a
combinatorial procedure named SELEX (Systematic Evolution of Ligands by Exponential …

Theranostic nanoplatforms represent an important tool in the diagnosis and therapy of many
major diseases, especially in the field of cancer theranostics, for which a myriad of …

In the past two decades, aptamers have emerged as a novel class of molecular recognition
probes comprising uniquely-folded short RNA or single-stranded DNA oligonucleotides that …

Conspectus As one of the most biocompatible and well-tolerated inorganic nanomaterials,
silica-based nanoparticles (SiNPs) have received extensive attention over the last several …

Facile fabrication of multimodal imaging probes is highly desired for bioimaging application
due to their integrated advantages of several imaging modalities. Here, we report a simple …

Epitope-based vaccine is a promising personalized cancer immunotherapy; however, a
simple and effective approach for its bulk manufacturing is challenging. Current vaccination …

Detection of sentinel lymph nodes (SLNs) is critical to guide the treatment of breast cancer.
However, distinguishing metastatic SLNs from normal and inflamed lymph nodes (LNs) …

Nucleic acid aptamers are small three-dimensional structures of oligonucleotides selected to
bind to a target of interest with high affinity and specificity. In vitro, aptamers already compete …

Positron emission tomography (PET) is an important modality in the field of molecular
imaging, which is gradually impacting patient care by providing safe, fast, and reliable …