Redox-responsive polycondensate neoepitope for enhanced personalized cancer vaccine

L Wei, Y Zhao, X Hu, L Tang - ACS central science, 2020 - ACS Publications
A versatile and highly effective platform remains a major challenge in the development of
personalized cancer vaccines. Here, we devised a redox-responsive polycondensate …

A smart nanoassembly for multistage targeted drug delivery and magnetic resonance imaging

Z Li, K Dong, S Huang, E Ju, Z Liu… - Advanced Functional …, 2014 - Wiley Online Library
Efficient delivery of DNA‐toxin anticancer drugs into nucleus of targeted tumor cells while
simultaneously minimizing the side effects to normal tissue is a major challenge for cancer …

Simultaneous fluorescence and chemiluminescence turned on by aggregation-induced emission for real-time monitoring of endogenous superoxide anion in live cells

J Niu, J Fan, X Wang, Y Xiao, X Xie, X Jiao… - Analytical …, 2017 - ACS Publications
Biological sensors with simultaneous turn-on signals of fluorescence (FL) and
chemiluminescence (CL) triggered by one single species are supposed to integrate …

Multimodality imaging agents with PET as the fundamental pillar

D Ni, EB Ehlerding, W Cai - Angewandte Chemie International …, 2019 - Wiley Online Library
Positron emission tomography (PET) provides quantitative information in vivo with ultra‐high
sensitivity but is limited by its relatively low spatial resolution. Therefore, PET has been …

Lipid–calcium phosphate nanoparticles for delivery to the lymphatic system and SPECT/CT imaging of lymph node metastases

YC Tseng, Z Xu, K Guley, H Yuan, L Huang - Biomaterials, 2014 - Elsevier
A lipid/calcium/phosphate (LCP) nanoparticle (NP) formulation (particle diameter∼ 25 nm)
with superior siRNA delivery efficiency was developed and reported previously. Here, we …

Aptamer-conjugated mesoporous silica nanoparticles for simultaneous imaging and therapy of cancer

S Vandghanooni, J Barar, M Eskandani… - TrAC Trends in Analytical …, 2020 - Elsevier
Mesoporous silica nanoparticles (MSNs) possess wide requirements for successful drug
delivery, due to their superior physicochemical properties such as the well-organized porous …

Targeted ultrasound‐assisted cancer‐selective chemical labeling and subsequent cancer imaging using click chemistry

H Wang, M Gauthier, JR Kelly, RJ Miller… - Angewandte Chemie …, 2016 - Wiley Online Library
Metabolic sugar labeling followed by the use of reagent‐free click chemistry is an
established technique for in vitro cell targeting. However, selective metabolic labeling of the …

[HTML][HTML] Gold-based inorganic nanohybrids for nanomedicine applications

X Ding, D Li, J Jiang - Theranostics, 2020 - ncbi.nlm.nih.gov
Noble metal Au nanoparticles have attracted extensive interests in the past decades, due to
their size and morphology dependent localized surface plasmon resonances. Their unique …

Bio-nano interface: The impact of biological environment on nanomaterials and their delivery properties

K Cai, AZ Wang, L Yin, J Cheng - Journal of Controlled Release, 2017 - Elsevier
The past several decades have witnessed the rapid development of nanomedicine (NM)
which integrates the advancement of various interdisciplinary areas of science, engineering …

Mesoporous silica nanoparticles: a smart nanosystem for management of breast cancer

N Poonia, V Lather, D Pandita - Drug Discovery Today, 2018 - Elsevier
Highlights•Stimuli-responsive MSNs can release drug at a target site by smart signal
switching.•MSNs possess great potential for better diagnosis of breast …