Vascular endothelial growth factor C levels are modulated by dietary salt intake in proteinuric chronic kidney disease patients and in healthy subjects

MCJ Slagman, AJ Kwakernaak… - Nephrology Dialysis …, 2012 - academic.oup.com
Background. Recent experimental findings demonstrate vascular endothelial growth factor C
(VEGF-C)-mediated water-free storage of salt in the interstitium, which prevents a salt …

Gender differences in response to acute and chronic angiotensin II infusion: a translational approach

TJ Toering, AM Van Der Graaf, FW Visser… - Physiological …, 2015 - Wiley Online Library
Women with renal disease progress at a slower rate to end stage renal disease than men.
As angiotensin II has both hemodynamic and direct renal effects, we hypothesized that the …

Magnetic Resonance Imaging–Derived Renal Oxygenation and Perfusion During Continuous, Steady‐State Angiotensin‐II Infusion in Healthy Humans

R van der Bel, BF Coolen, AJ Nederveen… - Journal of the …, 2016 - Am Heart Assoc
Background The role of kidney hypoxia is considered pivotal in the progression of chronic
kidney disease. A widely used method to assess kidney oxygenation is blood oxygen level …

Reducing salt intake for prevention of cardiovascular disease—times are changing

K Stolarz-Skrzypek, JA Staessen - Advances in chronic kidney disease, 2015 - Elsevier
The evidence relating blood pressure to salt intake in humans originates from population
studies and randomized clinical trials of interventions on dietary salt intake. Estimates from …

Renal hemodynamics and renin–angiotensin system activity in humans with multifocal renal artery fibromuscular dysplasia

DJL van Twist, AJHM Houben, MW de Haan… - Journal of …, 2016 - journals.lww.com
Background: Fibromuscular dysplasia (FMD) is the second most common cause of
renovascular hypertension. Nonetheless, knowledge on the renal microvasculature and …

Higher filtration fraction in formerly early-onset preeclamptic women without comorbidity

TJ Toering, AM van der Graaf… - American Journal …, 2015 - journals.physiology.org
Formerly preeclamptic women have an increased risk for developing end-stage renal
disease, which has been attributed to altered renal hemodynamics and abnormalities in the …

A computational model of the circulating renin-angiotensin system and blood pressure regulation

F Guillaud, P Hannaert - Acta biotheoretica, 2010 - Springer
The renin-angiotensin system (RAS) is critical in sodium and blood pressure (BP) regulation,
and in cardiovascular-renal (CVR) diseases and therapeutics. As a contribution to SAPHIR …

Race, obesity, and the renin-angiotensin-aldosterone system: treatment response in children with primary hypertension

AM South, L Arguelles, G Finer, CB Langman - Pediatric Nephrology, 2017 - Springer
Background Pediatric primary hypertension (HTN) is increasingly recognized, but the effect
of patient characteristics such as obesity and race on treatment outcomes is not well …

Влияние петлевых диуретиков с различным периодом полувыведения на динамику натрийуреза и показатели, характеризующие состояние …

ГП Арутюнов, ДО Драгунов… - Терапевтический архив, 2014 - cyberleninka.ru
Цель исследования. Изучение влияния петлевых диуретиков с различным периодом
полувыведения на изменения натрийуреза (НУ) у больных гипертонической болезнью …

Blood pressure, cardiovascular outcomes and sodium intake, a critical review of the evidence

K Stolarz-Skrzypek, Y Liu, L Thijs… - Acta Clinica …, 2012 - Taylor & Francis
Consideration of the role of NaCl (salt) in the pathogenesis and treatment of essential
hypertension is one of the overriding research themes both in experimental and clinical …