Calcinosis cutis: part I. Diagnostic pathway

N Reiter, L El-Shabrawi, B Leinweber… - Journal of the American …, 2011 - Elsevier
Calcinosis cutis is characterized by the deposition of insoluble calcium salts in the skin and
subcutaneous tissue. The syndrome is separated into five subtypes: dystrophic calcification …

[HTML][HTML] Genetic modulation of senescent phenotypes in Homo sapiens

GM Martin - Cell, 2005 - cell.com
Single-gene mutations can produce human progeroid syndromes—phenotypes that mimic
usual or" normative" aging. These can be divided into two classes—those that have their …

[HTML][HTML] Calcinosis cutis and calciphylaxis

D Jiménez-Gallo, L Ossorio-García… - Actas Dermo …, 2015 - Elsevier
Calcinosis cutis (CC) is defined as the deposition of calcium salts in the skin. The condition
is divided into 5 types: calciphylaxis and dystrophic, metastatic, idiopathic, and iatrogenic …

[HTML][HTML] Fibroblasts from different body parts exhibit distinct phenotypes in adult progeria Werner syndrome

H Kato, Y Maezawa, N Takayama, Y Ouchi… - Aging (Albany …, 2021 - ncbi.nlm.nih.gov
Werner syndrome (WS), also known as adult progeria, is characterized by accelerated aging
symptoms from a young age. Patients with WS experience painful intractable skin ulcers with …

Shp-1–dependent macrophage differentiation exacerbates virus-induced myositis

NB Watson, KM Schneider, PT Massa - The Journal of Immunology, 2015 - journals.aai.org
Virus-induced myositis is an emerging global affliction that remains poorly characterized
with few treatment options. Moreover, muscle-tropic viruses often spread to the CNS …

Clinical outcome and mechanism of soft tissue calcification in Werner syndrome

S Honjo, K Yokote, M Fujimoto, M Takemoto… - Rejuvenation …, 2008 - liebertpub.com
Werner syndrome (WS) is an autosomal recessive progeroid disorder caused by mutations
in RecQ DNA helicase. Ectopic soft tissue calcification is one of the well known symptoms in …

[HTML][HTML] Radiographic presentation of musculoskeletal involvement in Werner syndrome (adult progeria)

A David, M Vincent, PP Arrigoni, S Barbarot… - Diagnostic and …, 2017 - Elsevier
Werner syndrome (ie, adult progeria) is a rare autosomal recessive disorder caused by
mutations of the WRN gene, which is characterized by the premature appearance of features …

Management guideline for Werner syndrome 2020 8. Calcification in tendons associated with Werner syndrome

A Taniguchi, Y Tanaka, M Takemoto… - Geriatrics & …, 2021 - Wiley Online Library
Aim To clarify the diagnostic value of the calcification in the Achilles tendon for Werner
syndrome. Methods Calcification of the Achilles tendon in the plain radiograph was …

Наследственные синдромы с признаками преждевременного старения

ОО Голоунина, ВВ Фадеев… - Остеопороз и остеопатии, 2019 - cyberleninka.ru
Старение мультифакторный биологический процесс, неизбежно затрагивающий
каждого человека. Дегенеративные процессы, начинаясь на клеточном и молекулярном …

[HTML][HTML] Calcification in Werner syndrome associated with lymphatic vessels aging

H Ogata, S Akita, S Ikehara, K Azuma… - Aging (Albany …, 2021 - ncbi.nlm.nih.gov
In addition to the symptoms of aging, the main symptoms in Werner syndrome (WS), a
hereditary premature aging disease, include calcification of subcutaneous tissue with solid …