Malaria is a major infectious disease. In the last 10 years it has killed more than 20 million
people, mainly small children in Africa. The highly efficacious artemisinine combination …

Drug combination therapies have been devised to delay the development and spread of
resistant malaria parasites. However, poor design often leads to ineffective combinations …

The Great Failure of Malaria Control in Africa: A District Perspective from Burkina Faso | PLOS
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Background The use of drug combinations, including non-artemisinin-based and artemisinin-
based combination therapy (ACT), is a novel strategy that enhances therapeutic efficacy and …

Because of increasing resistance to 4-aminoquinolines in Papua New Guinea, combination
therapy of amodiaquine (AQ) or chloroquine (CQ) plus sulfadoxine-pyrimethamine (SP) was …

Abstract AIM: The Primary Medical Education (PRIME) program is an outpatient-based,
internal medicine residency track nested within the University of California, San Francisco …

In the absence of prompt and efficacious treatment, malaria patients may progress within a
few hours from having minor symptoms to severe disease and death. These last years have …

A large investment is required to develop, license and deploy a new antimalarial drug. Too
often, that investment has been rapidly devalued by the selection of parasite populations …

Drug resistant malaria was a major factor contributing to the failure of a worldwide campaign
to eradicate malaria in the last century, and now threatens the large investment being made …

Amodiaquine is a central drug in the new global strategy of combination therapies for the
control of malaria. Amodiaquine is mainly metabolized hepatically towards its major active …