All endocrine glands are susceptible to neoplastic growth, yet the health consequences of
these neoplasms differ between endocrine tissues. Pituitary neoplasms are highly prevalent …

Partial or complete deficiency of anterior or posterior pituitary hormone production leads to
central hypoadrenalism, central hypothyroidism, hypogonadotropic hypogonadism, growth …

Rationale and Objectives Ki67 proliferation index is associated with more aggressive tumor
behavior and recurrence of pituitary adenomas (PAs). Recently, radiomics and deep …

Objective To explore pituitary tumors by methylome and transcriptome signatures in a
heterogeneous ethnic population. Methods In this retrospective cross-sectional study …

Endocrine tumors derive from endocrine cells with high heterogeneity in function, structure
and embryology, and are characteristic of a marked diversity and tissue heterogeneity …

Background. Long noncoding RNAs (lncRNAs) play important roles in the tumorigenesis
and progression of various cancer types; however, their roles in the development of invasive …

Purpose Outcomes of patients with non-functioning pituitary adenomas categorized using
the 2004 and 2017 WHO classification systems are understudied. We report outcomes from …

Objective Pituitary tumours comprise a pathologically and clinically diverse group of
neoplasms. Classification frameworks have changed dramatically in the past two decades …

Objective: The Ki-67 index is an indicator of the active proliferation and aggressive behavior
of pituitary adenomas (PAs). Appropriate pre-and intra-operatives of the Ki-67 index can …

Purpose Prolactinoma is the most common type of pituitary adenoma. Most prolactinoma
need medical treatment, but some of them are aggressive and require surgery. In previous …