Dry powder inhaler formulation

MJ Telko, AJ Hickey - Respiratory care, 2005 - rc.rcjournal.com
A drug product combines pharmacologic activity with pharmaceutical properties. Desirable
performance characteristics are physical and chemical stability, ease of processing …

[HTML][HTML] Inhaled medication and inhalation devices for lung disease in patients with cystic fibrosis: a European consensus

H Heijerman, E Westerman, S Conway, D Touw… - Journal of Cystic …, 2009 - Elsevier
In cystic fibrosis inhalation of drugs for the treatment of CF related lung disease has been
proven to be highly effective. Consequently, an increasing number of drugs and devices …

Formulation design of dry powders for inhalation

JG Weers, DP Miller - Journal of pharmaceutical sciences, 2015 - Elsevier
Drugs for inhalation are no longer exclusively highly crystalline small molecules. They may
also be amorphous small molecules, peptides, antibodies, and myriad types of engineered …

The DiskusTM: a review of its position among dry powder inhaler devices

H Chrystyn - International journal of clinical practice, 2007 - Wiley Online Library
The use of dry powder inhalers (DPIs) to administer treatments for respiratory diseases has
increased significantly in recent years. There is now a wide range of DPIs available that vary …

Guidelines for aerosol devices in infants, children and adults: which to choose, why and how to achieve effective aerosol therapy

A Ari, JB Fink - Expert review of respiratory medicine, 2011 - Taylor & Francis
Multiple types of aerosol devices are commonly used for the administration of medical
aerosol therapy to patients with pulmonary diseases. All of these devices have been shown …

[HTML][HTML] Dry powder inhalation of colistin in cystic fibrosis patients: a single dose pilot study

EM Westerman, AH De Boer, PPH Le Brun… - Journal of Cystic …, 2007 - Elsevier
BACKGROUND: Dry powder inhalation (DPI) may be an alternative to nebulisation of drugs
in the treatment of chest infections in cystic fibrosis (CF) patients. In a pilot study the …

Can pharmacokinetic studies assess the pulmonary fate of dry powder inhaler formulations of fluticasone propionate?

G Hochhaus, MJ Chen, A Kurumaddali, U Schilling… - The AAPS journal, 2021 - Springer
In the context of streamlining generic approval, this study assessed whether
pharmacokinetics (PK) could elucidate the pulmonary fate of orally inhaled drug products …

Use of breath-actuated inhalers in patients with asthma and COPD–an advance in inhalational therapy: a systematic review

S Salvi, J Gogtay, B Aggarwal - Expert review of respiratory …, 2014 - Taylor & Francis
The pressurized metered dose inhalers and dry powder inhalers are the most widely used
devices for inhalation therapy in asthma and chronic obstructive pulmonary disease; each of …

Inhaler devices in infants and children: challenges and solutions

ML Everard - Journal of aerosol medicine, 2004 - liebertpub.com
THE ISSUES surrounding the use of inhaled ther-apy in children are essentially the same as
those in adults. Patients must be given a device that they can and will use effectively—the …

[PDF][PDF] Dry powder inhalers-an overview

M Alagusundaram, N Deepthi, S Ramkanth… - Int. J. Res. Pharm …, 2010 - researchgate.net
The drug product encompasses the pharmacologic activity with the pharmaceutical
properties. The ideal characteristics are physical and chemical stability, ease of processing …