The effectiveness and safety of generic drugs are backed by sound physicochemical control
and regulatory bioequivalence acceptance criteria. Statistical testing of bioequivalence …

Introduction Inhalation therapy is a cornerstone of treating patients with chronic obstructive
pulmonary disease (COPD). Inhaler devices might influence the effectiveness of inhalation …

The physical and chemical stability of dry powder aerosol formulations is an essential
component in the development of an inhaled therapeutic. The pharmaceutical processing …

Purpose This study investigated the effect of oropharyngeal geometry on inhaled aerosol
characteristics via pressurised metered dose inhalers (pMDIs), both with or without spacers …

Methods: We recruited control subjects (Controls, n= 17) and patients with stable COPD (S-
COPD, n= 13) and those during an acute exacerbation (AECOPD, n= 12). Standard …

Background: The lung dose of nebulized drugs for spontaneous breathing is influenced by
breathing patterns and nebulizer performance. This study aimed to develop a system for …

In view of the limited sensitivity of traditional therapeutic effect models to compare generic
and reference orally inhaled products (OIPs), the revised European regulatory guidance on …

54 увеличению эффективности более чем в 2 раза при уменьшении риска осложнений
со стороны верхних дыха тельных путей [10, 11]. Легочная депозиция препарата может …

Frequent administration of aerosolized drugs to pediatric patients is often for facilitating
mucus clearance, preventing and treating infections, enhancing pulmonary blood flow, etc …

A Dry powder inhaler (DPI) is a dry-powder product that provides medicine to the lungs.
Asthma, bronchitis nd COPD are common in treating breathing disorders. DPI interests have …