Metformin: a novel weapon against inflammation
B Bai, H Chen - Frontiers in pharmacology, 2021 - frontiersin.org
It has become widely accepted that inflammation is a driving force behind a variety of
chronic diseases, such as cardiovascular disease, diabetes, kidney disease, cancer …
chronic diseases, such as cardiovascular disease, diabetes, kidney disease, cancer …
Metformin for cardiovascular protection, inflammatory bowel disease, osteoporosis, periodontitis, polycystic ovarian syndrome, neurodegeneration, cancer …
M Ala, M Ala - ACS pharmacology & translational science, 2021 - ACS Publications
Diabetes is accompanied by several complications. Higher prevalence of cancers,
cardiovascular diseases, chronic kidney disease (CKD), obesity, osteoporosis, and …
cardiovascular diseases, chronic kidney disease (CKD), obesity, osteoporosis, and …
Serum albumin levels: a biomarker to be repurposed in different disease settings in clinical practice
Serum albumin (ALB), one of the most important proteins in human physiology, has the main
functions of maintaining plasma oncotic pressure and plasma volume, transporting …
functions of maintaining plasma oncotic pressure and plasma volume, transporting …
Ibuprofen induces ferroptosis of glioblastoma cells via downregulation of nuclear factor erythroid 2-related factor 2 signaling pathway
X Gao, N Guo, H Xu, T Pan, A Yan, Y Mi, L Xu - Anti-cancer …, 2020 - journals.lww.com
Ferroptosis is a newly discovered type of cell death decided by iron-dependent lipid
peroxidation, but its role in glioblastoma cell death remains unclear. Ibuprofen, a …
peroxidation, but its role in glioblastoma cell death remains unclear. Ibuprofen, a …
Polymorphism of toll-like receptor genes and autoimmune endocrine diseases
KA Dvornikova, EY Bystrova, ON Platonova… - Autoimmunity …, 2020 - Elsevier
In recent years, there has been a significant amount of interest and vigorous studies on
mutations related to innate immunity receptor genes such as Toll-like receptors (TLR), which …
mutations related to innate immunity receptor genes such as Toll-like receptors (TLR), which …
Type 2 diabetes mellitus and cancer: Epidemiology, physiopathology and prevention
C Rey-Reñones, JM Baena-Díez, I Aguilar-Palacio… - Biomedicines, 2021 - mdpi.com
Individuals with type 2 diabetes mellitus are at greater risk of developing cancer and of dying
from it. Both diseases are age-related, contributing to the impact of population aging on the …
from it. Both diseases are age-related, contributing to the impact of population aging on the …
[HTML][HTML] Metformin generates profound alterations in systemic and tumor immunity with associated antitumor effects
R Veeramachaneni, W Yu, JM Newton… - … for immunotherapy of …, 2021 - ncbi.nlm.nih.gov
Background Metformin is a commonly used antidiabetic medication which has demonstrated
promise as an anticancer agent alone and in combination with conventional treatment …
promise as an anticancer agent alone and in combination with conventional treatment …
[HTML][HTML] The Relationship between metformin consumption and cancer risk: an updated umbrella review of systematic reviews and meta-analyses
Background: Considering that metformin is widely used in the treatment of diabetes, and its
protective role against various malignancies, the strength and validity of the available …
protective role against various malignancies, the strength and validity of the available …
Autoimmune diseases and hematological malignancies: exploring the underlying mechanisms from epidemiological evidence
K Hemminki, W Huang, J Sundquist… - Seminars in cancer …, 2020 - Elsevier
Autoimmune diseases are characterized by the irregular functioning of the immune system
that leads to the loss of tolerance to self-antigens. The underlying nature of autoimmune …
that leads to the loss of tolerance to self-antigens. The underlying nature of autoimmune …
Effects of inflammatory and anti-inflammatory environments on the macrophage mitochondrial function
D Ji, J Yin, D Li, C Zhu, J Ye, Y Pan - Scientific Reports, 2020 - nature.com
Mitochondrial response to inflammation is crucial in the metabolic adaptation to infection.
This study aimed to explore the mitochondrial response under inflammatory and anti …
This study aimed to explore the mitochondrial response under inflammatory and anti …