Objective To assess the efficacy and harms of adding medical cannabis to prescription
opioids among people living with chronic pain. Design Systematic review. Data sources …

Cannabinoids, including those found in cannabis, have shown promise as potential
therapeutics for numerous health issues, including pathological pain and diseases that …

GABA is a major inhibitory neurotransmitter that regulates the balance between excitatory
and inhibitory circuits in the human nervous system. The GABA receptors are divided into …

Background: Chronic opioid therapy (COT) has been used to treat many chronic pain
conditions even with poor evidence for its long-term effectiveness. Medical cannabis has …

The proportion of older adults using medical cannabis is rising. Therefore, we aimed to
assess the effects of herbal medical cannabis on the functional status of older adults. We …

There is a growing body of evidence that cannabis may be effective as an analgesic with
potential to reduce opioid usage in chronic pain. This review synthesizes the available …

Background With legal access to medical cannabis in Canada since 2001, there is a need to
fully characterize its use at both the individual and population levels. We draw on data from …

Background Opioids continue to be widely prescribed for chronic noncancer pain, despite
the awareness that opioids provide only short-time pain relief, lead to dose accumulation …

Background Little is known about how cannabis knowledge and attitudes impact cannabis
use behavior. Objective To test the knowledge-attitudes-behavior paradigm in active adult …

Background In humans, the effect of cannabis on ventilatory control is poorly studied, and
consequently, the effect of Δ 9-tetrahydrocannabinol (THC) remains unknown, particularly …