The senescence of bone marrow mesenchymal stem cells (BMSCs) is the basis of senile
osteoporosis (SOP). Targeting BMSCs senescence is of paramount importance for …

Organ degeneration refers to the gradual decline in organ function and structure
deterioration that occurs during aging, which represents the greatest risk factor for various …

Aging is a natural phenomenon characterized by a progressive decline in physiological
integrity, leading to a deterioration of cognitive function and increasing the risk of suffering …

Cardiovascular diseases (CVDs) are the leading cause of death world-wide. Thus,
diagnosing and treating CVD remains at the forefront for clinicians while identifying …

The skeleton is an important structural and metabolic organ in human body, while aging is
the physiological basis for degenerative skeletal diseases. China has the largest aging …

The proportion of patients diagnosed with cancer has been shown to rise with the increasing
aging global population. Advanced age is a major risk factor for morbidity and mortality in …

The maintenance of genome integrity through generations is largely determined by the
stability of telomeres. Increasing evidence suggests that telomere dysfunction may trigger …

This scoping review aimed to summarise the effects of the ketone body β-hydroxybutyrate.
The review details the revealed pathways and functional properties following its intervention …

The gut is the largest digestive and absorptive organ, which is essential for induction of
mucosal and systemic immune responses, and maintenance of metabolic-immune …

Aging is closely related to redox regulation. In our previous work, we proposed a new
concept,“redox-stress response capacity (RRC),” and found that the decline in RRC was a …