[HTML][HTML] Anaplastic thyroid cancer: molecular pathogenesis and emerging therapies
RC Smallridge, LA Marlow… - Endocrine-related …, 2009 - erc.bioscientifica.com
Anaplastic thyroid cancer (ATC) is a rare malignancy. While external beam radiation therapy
has improved locoregional control, the median survival of∼ 4 months has not changed in …
has improved locoregional control, the median survival of∼ 4 months has not changed in …
Update on anaplastic thyroid carcinoma: morphological, molecular, and genetic features of the most aggressive thyroid cancer
M Ragazzi, A Ciarrocchi, V Sancisi… - International journal …, 2014 - Wiley Online Library
Anaplastic thyroid carcinoma (ATC) is the most aggressive form of thyroid cancer. It shows a
wide spectrum of morphological presentations and the diagnosis could be challenging due …
wide spectrum of morphological presentations and the diagnosis could be challenging due …
Genomic and transcriptomic hallmarks of poorly differentiated and anaplastic thyroid cancers
I Landa, T Ibrahimpasic, L Boucai… - The Journal of …, 2016 - Am Soc Clin Investig
BACKGROUND. Poorly differentiated thyroid cancer (PDTC) and anaplastic thyroid cancer
(ATC) are rare and frequently lethal tumors that so far have not been subjected to …
(ATC) are rare and frequently lethal tumors that so far have not been subjected to …
American Thyroid Association guidelines for management of patients with anaplastic thyroid cancer
RC Smallridge, KB Ain, SL Asa, KC Bible, JD Brierley… - Thyroid, 2012 - liebertpub.com
Background: Anaplastic thyroid cancer (ATC) is a rare but highly lethal form of thyroid
cancer. Rapid evaluation and establishment of treatment goals are imperative for optimum …
cancer. Rapid evaluation and establishment of treatment goals are imperative for optimum …
Genetic alterations in poorly differentiated and undifferentiated thyroid carcinomas
Thyroid gland presents a wide spectrum of tumours derived from follicular cells that range
from well differentiated, papillary and follicular carcinoma (PTC and FTC, respectively) …
from well differentiated, papillary and follicular carcinoma (PTC and FTC, respectively) …
An evidence-based approach to familial nonmedullary thyroid cancer: screening, clinical management, and follow-up
Approximately 5% of nonmedullary thyroid cancers are of familial origin. When two or more
family members are diagnosed with nonmedullary thyroid cancer in the absence of other …
family members are diagnosed with nonmedullary thyroid cancer in the absence of other …
Intragenic mutations in thyroid cancer
M Sobrinho-Simoes, V Maximo, AS Rocha… - … and metabolism clinics …, 2008 - Elsevier
The close genotype-phenotype relationship that characterizes thyroid oncology stimulated
the authors to address this article by using a mixed, genetic and phenotypic approach. As …
the authors to address this article by using a mixed, genetic and phenotypic approach. As …
FOXA1 Is a Potential Oncogene in Anaplastic Thyroid Carcinoma
C Nucera, J Eeckhoute, S Finn, JS Carroll… - Clinical Cancer …, 2009 - AACR
Purpose: FOXA1 is a mammalian endodermal transcription factor belonging to the human
forkhead box gene family that plays a role in certain tumor types. Here, we investigated the …
forkhead box gene family that plays a role in certain tumor types. Here, we investigated the …
Identification of targetable lesions in anaplastic thyroid cancer by genome profiling
N Ravi, M Yang, S Gretarsson, C Jansson, N Mylona… - Cancers, 2019 - mdpi.com
Anaplastic thyroid cancer (ATC) is a rare and extremely malignant tumor with no available
cure. The genetic landscape of this malignancy has not yet been fully explored. In this study …
cure. The genetic landscape of this malignancy has not yet been fully explored. In this study …
Genomic hallmarks of thyroid neoplasia
TJ Giordano - Annual Review of Pathology: Mechanisms of …, 2018 - annualreviews.org
The genomic landscape of thyroid cancers that are derived from follicular cells has been
substantially elucidated through the coordinated application of high-throughput genomic …
substantially elucidated through the coordinated application of high-throughput genomic …