Overgrowth syndromes are a heterogeneous group of rare disorders characterized by
generalized or segmental excessive growth commonly associated with additional features …

Simple Summary Beckwith–Wiedemann syndrome (BWS, OMIM 130650) is an inborn
overgrowth disorder caused by molecular alterations in chromosome 11p15. 5. These …

Genomic imprinting, a phenomenon in which the two parental alleles are regulated
differently, is observed in mammals, marsupials and a few other species, including seed …

Genomic imprinting is a term used for an intergenerational epigenetic inheritance and
involves a subset of genes expressed in a parent-of-origin-dependent way. Imprinted genes …

Purpose It is well documented that patients with Beckwith–Wiedemann spectrum (BWS)
have a significantly higher risk of developing Wilms tumor (WT) than the general population …

Beckwith–Wiedemann Spectrum (BWSp) is the most common epigenetic childhood cancer
predisposition disorder. BWSp is caused by (epi) genetic changes affecting the BWS critical …

Epigenetic diseases can be produced by a stable alteration, called an epimutation, in DNA
methylation, in which epigenome alterations are directly involved in the underlying …

Simple Summary Beckwith–Wiedemann syndrome (BWS) is an overgrowth disorder caused
by imprinting or genetic alterations at the 11p15. 5 locus. BWS is considered a spectrum …

Abstract Background Beckwith–Wiedemann syndrome (BWS) is a rare overgrowth
syndrome characterized by congenital malformations and predisposition to embryonic …

Objectives: Review the etiology of omphalocele. Describe the presentation of omphalocele.
Summarize the treatment of omphalocele. Explain the importance of improving care …