[HTML][HTML] Advances in drug delivery to atherosclerosis: Investigating the efficiency of different nanomaterials employed for different type of drugs

B Perera, Y Wu, NT Nguyen, HT Ta - Materials Today Bio, 2023 - Elsevier
Atherosclerosis is the build-up of fatty deposits in the arteries. Atherosclerosis is the main
underlying cause of cardiovascular diseases and the leading cause of global morbidity and …

Advances in HDL: much more than lipid transporters

S Ben-Aicha, L Badimon, G Vilahur - International Journal of Molecular …, 2020 - mdpi.com
High Density Lipoprotein (HDL) particles, beyond serving as lipid transporters and playing a
key role in reverse cholesterol transport, carry a highly variable number of proteins, micro …

Site‐specific microRNA‐33 antagonism by pH‐responsive nanotherapies for treatment of atherosclerosis via regulating cholesterol efflux and adaptive immunity

C Li, Y Dou, Y Chen, Y Qi, L Li, S Han… - Advanced functional …, 2020 - Wiley Online Library
Atherosclerosis remains the leading cause of a broad spectrum of deadliest cardiovascular
diseases. MicroRNA‐33 is a new therapeutic target for atherosclerosis due to its diverse …

Brothers in arms: ABCA1-and ABCG1-mediated cholesterol efflux as promising targets in cardiovascular disease treatment

SJCM Frambach, R de Haas, JAM Smeitink… - Pharmacological …, 2020 - ASPET
Atherosclerosis is a leading cause of cardiovascular disease worldwide, and
hypercholesterolemia is a major risk factor. Preventive treatments mainly focus on the …

Epigenetics and precision medicine in cardiovascular patients: from basic concepts to the clinical arena

S Costantino, P Libby, R Kishore, JC Tardif… - European heart …, 2018 - academic.oup.com
Cardiovascular diseases (CVDs) remain the leading cause of mortality worldwide and also
inflict major burdens on morbidity, quality of life, and societal costs. Considering that CVD …

microRNAs associated with carotid plaque development and vulnerability: the clinician's perspective

R Badacz, T Przewłocki, J Legutko, K Żmudka… - International Journal of …, 2022 - mdpi.com
Ischemic stroke (IS) related to atherosclerosis of large arteries is one of the leading causes
of mortality and disability in developed countries. Atherosclerotic internal carotid artery …

microRNAs in lipoprotein and lipid metabolism: from biological function to clinical application

V Desgagné, L Bouchard, R Guérin - Clinical Chemistry and …, 2017 - degruyter.com
Abstract microRNAs (miRNAs) are short (~ 22 nucleotides), non-coding, single-stranded
RNA molecules that regulate the expression of target genes by partial sequence-specific …

[HTML][HTML] miR-33a is a tumor suppressor microRNA that is decreased in prostate cancer

OF Karatas, J Wang, L Shao, M Ozen, Y Zhang… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Prostate cancer is one of the most frequently diagnosed neoplasms among men worldwide.
MicroRNAs (miRNAs) are involved in numerous important cellular processes including …

High-density lipoprotein metabolism and function in cardiovascular diseases: what about aging and diet effects?

M Morvaridzadeh, N Zoubdane, J Heshmati, M Alami… - Nutrients, 2024 - mdpi.com
Cardiovascular diseases (CVDs) have become the leading global cause of mortality,
prompting a heightened focus on identifying precise indicators for their assessment and …

Connecting epigenetics and inflammation in vascular senescence: state of the art, biomarkers and senotherapeutics

O Fraile-Martinez, D De Leon-Oliva, DL Boaru… - Frontiers in …, 2024 - frontiersin.org
Vascular diseases pose major health challenges, and understanding their underlying
molecular mechanisms is essential to advance therapeutic interventions. Cellular …