Recent research suggests that epigenetics, especially DNA methylation, plays a mechanistic
role in aging. Epigenetic clocks, which measure changes in a few hundred specific CpG …

A deeper understanding of the pathomechanisms leading to stress-related psychiatric
disorders is important for the development of more efficient preventive and therapeutic …

Diabetic kidney disease (DKD) is the leading cause of chronic kidney disease and end-
stage renal disease. The natural history of DKD includes glomerular hyperfiltration …

Fibrosis, a common process of chronic inflammatory diseases, is defined as a repair
response disorder when organs undergo continuous damage, ultimately leading to scar …

Understanding the evolutionary and ecological roles of'non-genetic'inheritance (NGI) is
daunting due to the complexity and diversity of epigenetic mechanisms. We draw on insights …

Epigenetic modifications established during gametogenesis regulate transcription and other
nuclear processes in gametes, but also have influences in the zygote, embryo and postnatal …

Ageing, a leading cause of the decline/deficits in human learning, memory, and cognitive
abilities, is a major risk factor for age-associated neurodegenerative disorders such as …

Alzheimer's disease (AD) is the most common neurodegenerative disease, which severely
threatens the health of the elderly and causes significant economic and social burdens. The …

In higher organisms, all cells share the same genome, but every cell expresses only a
limited and specific set of genes that defines the cell type. During cell division, not only the …

Epigenetic changes are required for normal development, yet the nature and respective
contribution of factors that drive epigenetic variation in humans remain to be fully …