Akkermansia muciniphila: paradigm for next-generation beneficial microorganisms

PD Cani, C Depommier, M Derrien, A Everard… - Nature Reviews …, 2022 - nature.com
Ever since Akkermansia muciniphila was discovered and characterized two decades ago,
numerous studies have shown that the lack or decreased abundance of this commensal …

Akkermansia muciniphila and Gut Immune System: A Good Friendship That Attenuates Inflammatory Bowel Disease, Obesity, and Diabetes

VF Rodrigues, J Elias-Oliveira, ÍS Pereira… - Frontiers in …, 2022 - frontiersin.org
Akkermansia muciniphila is a Gram-negative anaerobic mucus-layer-degrading bacterium
that colonizes the intestinal mucosa of humans and rodents. Metagenomic data have shown …

Akkermansia muciniphila secretes a glucagon-like peptide-1-inducing protein that improves glucose homeostasis and ameliorates metabolic disease in mice

HS Yoon, CH Cho, MS Yun, SJ Jang, HJ You… - Nature …, 2021 - nature.com
The gut microbiota, which includes Akkermansia muciniphila, is known to modulate energy
metabolism, glucose tolerance, immune system maturation and function in humans …

Urinary extracellular vesicles: A position paper by the Urine Task Force of the International Society for Extracellular Vesicles

U Erdbrügger, CJ Blijdorp, IV Bijnsdorp… - Journal of …, 2021 - Wiley Online Library
Urine is commonly used for clinical diagnosis and biomedical research. The discovery of
extracellular vesicles (EV) in urine opened a new fast‐growing scientific field. In the last …

Bacterial outer membrane vesicles: from discovery to applications

MG Sartorio, EJ Pardue, MF Feldman… - Annual review of …, 2021 - annualreviews.org
Secretion of cellular components across the plasma membrane is an essential process that
enables organisms to interact with their environments. Production of extracellular vesicles in …

Microbiota‐derived extracellular vesicles in interkingdom communication in the gut

N Díaz‐Garrido, J Badia… - Journal of Extracellular …, 2021 - Wiley Online Library
The intestine is fundamental in controlling human health. Intestinal epithelial and immune
cells are continuously exposed to millions of microbes that greatly impact on intestinal …

Differences in gut microbiota in patients with vs without inflammatory bowel diseases: a systematic review

R Pittayanon, JT Lau, GI Leontiadis, F Tse, Y Yuan… - Gastroenterology, 2020 - Elsevier
Background & Aims Altering the intestinal microbiota has been proposed as a treatment for
inflammatory bowel diseases (IBDs), but there are no established associations between …

Polyethylene microplastics affect the distribution of gut microbiota and inflammation development in mice

B Li, Y Ding, X Cheng, D Sheng, Z Xu, Q Rong, Y Wu… - Chemosphere, 2020 - Elsevier
Environmental pollution caused by plastics has become a public health problem. However,
the effect of microplastics on gut microbiota, inflammation development and their underlying …

Postbiotics and their potential applications in early life nutrition and beyond

CAM Wegh, SY Geerlings, J Knol, G Roeselers… - International journal of …, 2019 - mdpi.com
Postbiotics are functional bioactive compounds, generated in a matrix during fermentation,
which may be used to promote health. The term postbiotics can be regarded as an umbrella …

[HTML][HTML] Mechanisms regulating intestinal barrier integrity and its pathological implications

C Chelakkot, J Ghim, SH Ryu - Experimental & molecular medicine, 2018 - nature.com
The gastrointestinal tract is a specialized organ in which dynamic interactions between host
cells and the complex environment occur in addition to food digestion. Together with the …