Targeting noncoding RNAs to reactivate or eliminate latent HIV reservoirs

N Beliakova-Bethell - Current Opinion in HIV and AIDS, 2024 - journals.lww.com
Comprehensive functional screens to uncover all ncRNAs that regulate HIV expression and
the detailed exploration of their mechanisms of action in relevant cell types are needed to …

[HTML][HTML] Breaking the Silence: Regulation of HIV Transcription and Latency on the Road to a Cure

NN Duggan, T Dragic, SK Chanda, L Pache - Viruses, 2023 - mdpi.com
Antiretroviral therapy (ART) has brought the HIV/AIDS epidemic under control, but a curative
strategy for viral eradication is still needed. The cessation of ART results in rapid viral …

Human and Viral microRNA Expression in Acute and Chronic HIV Infections

E Lazzari, G Rozera, R Gagliardini, R Esvan, A Mondi… - Viruses, 2024 - mdpi.com
Human and viral microRNAs (miRNAs) are involved in the regulation of gene transcription,
and the establishment of their profiles in acute (AHI) and chronic (CHI) HIV infections may …

[HTML][HTML] Direct and indirect effects of CYTOR lncRNA regulate HIV gene expression

A Kuzmina, L Sadhu, M Hasanuzzaman… - PLoS …, 2024 - journals.plos.org
The implementation of antiretroviral therapy (ART) has effectively restricted the transmission
of Human Immunodeficiency Virus (HIV) and improved overall clinical outcomes. However, a …

[HTML][HTML] MicroRNAs and long non-coding RNAs during transcriptional regulation and latency of HIV and HTLV

SP Alpuche-Lazcano, RJ Scarborough, A Gatignol - Retrovirology, 2024 - Springer
Human immunodeficiency virus (HIV) and human T cell leukemia virus (HTLV) have
replicative and latent stages of infection. The status of the viruses is dependent on the cells …