Uropathogenic Escherichia coli (UPEC) is a causative agent in the vast majority of urinary
tract infections (UTIs), including cystitis and pyelonephritis, and infectious complications …

The urinary tract is a common site of bacterial infections; nearly half of all women experience
at least one urinary tract infection (UTI) during their lifetime. These infections are classified …

Type 1 fimbriae are adhesion organelles expressed by many Gram-negative bacteria. They
facilitate adherence to mucosal surfaces and inflammatory cells in vitro, but their contribution …

Pathogenic bacteria that penetrate the intestinal epithelial barrier stimulate an inflammatory
response in the adjacent intestinal mucosa. The present studies asked whether colon …

Myeloid cell activation by lipopolysaccharides (LPS) involves two proteins, plasma LPS-
binding protein (LBP) and cell-membrane CD14. Cell membrane CD14, anchored by a …

Strains of uropathogenic Escherichia coli (UPEC) are the causative agents in the vast
majority of all urinary tract infections. Upon entering the urinary tract, UPEC strains face a …

Uropathogenic Escherichia coli (UPEC) proliferate within superficial bladder umbrella cells
to form intracellular bacterial communities (IBCs) during early stages of urinary tract …

Objective The effects of interleukin (IL)-6 in the injured patient are examined in an attempt to
clarify the potential pathophysiologic role of IL-6 in the response to injury. Summary …

Bacterial invasion of mucosal surfaces results in a rapid influx of polymorphonuclear
leukocytes. The chemotactic stimulus responsible for this response is not known. Since …

Background: To characterize the role of intestinal epithelial cells in mucosal host defense,
we have examined constitutive cytokine expression and regulated expression of interleukin …