Pathogenicity and virulence of Burkholderia pseudomallei

NM Bzdyl, CL Moran, J Bendo, M Sarkar-Tyson - Virulence, 2022 - Taylor & Francis
The soil saprophyte, Burkholderia pseudomallei, is the causative agent of melioidosis, a
disease endemic in South East Asia and northern Australia. Exposure to B. pseudomallei by …

Melioidosis: molecular aspects of pathogenesis

JK Stone, D DeShazer, PJ Brett… - Expert review of anti …, 2014 - Taylor & Francis
Burkholderia pseudomallei is a gram-negative bacterium that causes melioidosis, a
multifaceted disease that is highly endemic in southeast Asia and northern Australia. This …

[HTML][HTML] Type III Secretion in the Melioidosis Pathogen Burkholderia pseudomallei

CW Vander Broek, JM Stevens - Frontiers in cellular and infection …, 2017 - frontiersin.org
Burkholderia pseudomallei is a Gram-negative intracellular pathogen and the causative
agent of melioidosis, a severe disease of both humans and animals. Melioidosis is an …

Burkholderia pseudomallei Adaptation for Survival in Stressful Conditions

T Duangurai, N Indrawattana… - BioMed research …, 2018 - Wiley Online Library
Burkholderia pseudomallei is a Gram‐negative bacterium that causes melioidosis, which
can be fatal in humans. Melioidosis is prevalent in the tropical regions of Southeast Asia and …

Transitioning from soil to host: comparative transcriptome analysis reveals the Burkholderia pseudomallei response to different niches

AK Ghazali, M Firdaus-Raih, A Uthaya Kumar… - Microbiology …, 2023 - Am Soc Microbiol
Burkholderia pseudomallei, a soil and water saprophyte, is responsible for the tropical
human disease melioidosis. A hundred years since its discovery, there is still much to learn …

[HTML][HTML] Characterization and analysis of the Burkholderia pseudomallei BsaN virulence regulon

Y Chen, I Schröder, CT French, A Jaroszewicz… - BMC microbiology, 2014 - Springer
Background Burkholderia pseudomallei is a facultative intracellular pathogen and the
causative agent of melioidosis. A conserved type III secretion system (T3SS3) and type VI …

[HTML][HTML] Quantitative Proteomic Analysis of Burkholderia pseudomallei Bsa Type III Secretion System Effectors Using Hypersecreting Mutants [S]

CW Vander Broek, KJ Chalmers, MP Stevens… - Molecular & Cellular …, 2015 - ASBMB
Burkholderia pseudomallei is an intracellular pathogen and the causative agent of
melioidosis, a severe disease of humans and animals. One of the virulence factors critical for …

[HTML][HTML] Inhibition of macrophage infectivity potentiator in Burkholderia pseudomallei suppresses pro-inflammatory responses in murine macrophages

J Iwasaki, NM Bzdyl, DJM Lin-Sullivan… - Frontiers in Cellular …, 2024 - frontiersin.org
Introduction Melioidosis, caused by the Gram-negative bacterium Burkholderia
pseudomallei, is a disease endemic in many tropical countries globally. Clinical …

Burkholderia pseudomallei pathogenesis and survival in different niches

CH Yip, AK Ghazali, S Nathan - Biochemical Society …, 2020 - portlandpress.com
Burkholderia pseudomallei (Bp) is the causative agent of melioidosis, a disease of the
tropics with high clinical mortality rates. To date, no vaccines are approved for melioidosis …

pH alkalinization by chloroquine suppresses pathogenic Burkholderia type 6 secretion system 1 and multinucleated giant cells

J Chua, JL Senft, SJ Lockett, PJ Brett… - Infection and …, 2017 - Am Soc Microbiol
Burkholderia mallei and B. pseudomallei cause glanders and melioidosis, respectively, in
humans and animals. A hallmark of pathogenesis is the formation of granulomas containing …