[HTML][HTML] Sperm DNA fragmentation: a new guideline for clinicians
A Agarwal, A Majzoub, S Baskaran… - The world journal of …, 2020 - ncbi.nlm.nih.gov
Sperm DNA integrity is crucial for fertilization and development of healthy offspring. The
spermatozoon undergoes extensive molecular remodeling of its nucleus during later phases …
spermatozoon undergoes extensive molecular remodeling of its nucleus during later phases …
Reactive oxygen species impact on sperm DNA and its role in male infertility
Reactive oxygen species (ROS) have been extensively studied as a cause of male infertility.
Excessive levels of ROS coupled with a deficiency in antioxidants can lead to oxidative …
Excessive levels of ROS coupled with a deficiency in antioxidants can lead to oxidative …
[HTML][HTML] Mitochondria functionality and sperm quality
A Amaral, B Lourenço, M Marques… - …, 2013 - rep.bioscientifica.com
Although mitochondria are best known for being the eukaryotic cell powerhouses, these
organelles participate in various cellular functions besides ATP production, such as calcium …
organelles participate in various cellular functions besides ATP production, such as calcium …
Role of sperm chromatin abnormalities and DNA damage in male infertility
Sperm DNA integrity is essential for the accurate transmission of genetic information. It has a
highly compact and complex structure and is capable of decondensation—features that must …
highly compact and complex structure and is capable of decondensation—features that must …
Oxidative stress & male infertility
K Makker, A Agarwal, R Sharma - Indian Journal of Medical …, 2009 - journals.lww.com
The male factor is considered a major contributory factor to infertility. Apart from the
conventional causes for male infertility such as varicocoele, cryptorchidism, infections …
conventional causes for male infertility such as varicocoele, cryptorchidism, infections …
Sperm selection in natural conception: what can we learn from Mother Nature to improve assisted reproduction outcomes?
BACKGROUND In natural conception only a few sperm cells reach the ampulla or the site of
fertilization. This population is a selected group of cells since only motile cells can pass …
fertilization. This population is a selected group of cells since only motile cells can pass …
Spermatogenesis, DNA damage and DNA repair mechanisms in male infertility
S Gunes, M Al-Sadaan, A Agarwal - Reproductive biomedicine online, 2015 - Elsevier
Spermatogenesis is a complex process of proliferation and differentiation during male germ
cell development involving mitosis, meiosis and spermiogenesis. Endogenous and …
cell development involving mitosis, meiosis and spermiogenesis. Endogenous and …
The importance of folate, zinc and antioxidants in the pathogenesis and prevention of subfertility
IMW Ebisch, CMG Thomas, WHM Peters… - Human reproduction …, 2007 - academic.oup.com
Current treatments of subfertile couples are usually empiric, as the true cause of subfertility
often remains unknown. Therefore, we outline the role of nutritional and biochemical factors …
often remains unknown. Therefore, we outline the role of nutritional and biochemical factors …
DNA damage to spermatozoa has impacts on fertilization and pregnancy
SEM Lewis, RJ Aitken - Cell and tissue research, 2005 - Springer
DNA damage in the male germ line has been associated with poor semen quality, low
fertilization rates, impaired preimplantation development, increased abortion and an …
fertilization rates, impaired preimplantation development, increased abortion and an …
The combined human sperm proteome: cellular pathways and implications for basic and clinical science
BACKGROUND The human sperm cell is very well suited for proteomic studies, as it is
accessible, can be easily purified and is believed to be transcriptionally and translationally …
accessible, can be easily purified and is believed to be transcriptionally and translationally …