In this context, sperm chromatin abnormalities have been studied extensively in past
decades as a cause of male infertility. The authors provide the rationale for sperm chromatin …

Purpose Sperm DNA fragmentation has been suggested as a marker for infertility diagnosis
and prognosis. Hence, understanding its impact on male physiology and post-genomic …

OBJECTIVE: To provide evidence that the Fas-mediated apoptotic process may participate
in developing hypospermatogenesis, such as maturation arrest (MA) and Sertoli cell–only …

Although intracytoplasmic sperm injection (ICSI) is now a widely-used technique, it is still of
interest to improve our knowledge as to which is the best spermatozoon to be selected for …

Defective mammalian spermatozoa become ubiquitinated during epididymal passage, a
mechanism that may mark the abnormal spermatozoa for proteolytic destruction (Sutovsky et …

Background Externalization of phosphatidylserine (EPS) occurs in apoptotic-like
spermatozoa and could be used to remove them from sperm preparations to enhance sperm …

Purpose To observe changes in semen parameters, sperm DNA integrity, chromatin
condensation and cysteinyl aspartate-spicific proteinases (Caspase-3) in adult healthy men …

The signaling pathways that characterize the process of capacitation of human spermatozoa
are still largely unknown. Modifications in the lipid architecture of the sperm plasma …

Human sperm express two types of protamine: protamine 1 (P1) and the family of protamine
2 (P2) proteins, with P1 and P2 normally existing in a ratio of approximately 1: 1. Both the …

Recent studies have evaluated the use of magnetic‐activated cell sorting (MACS) to reduce
apoptotic spermatozoa and improve sperm quality. However, the efficiency of using MACS …