The uniqueness of albumin as a carrier in nanodrug delivery

A Spada, J Emami, JA Tuszynski… - Molecular …, 2021 - ACS Publications
Albumin is an appealing carrier in nanomedicine because of its unique features. First, it is
the most abundant protein in plasma, endowing high biocompatibility, biodegradability …

Structure, enzymatic activities, glycation and therapeutic potential of human serum albumin: A natural cargo

G Rabbani, SN Ahn - International journal of biological macromolecules, 2019 - Elsevier
Human serum albumin (HSA) is an opulent, non-glycosylated, most versatile carrier protein
in plasma possessing multiple functions. HSA has the ability to interact with a variety of …

Emerging nanotechnology and advanced materials for cancer radiation therapy

G Song, L Cheng, Y Chao, K Yang, Z Liu - Advanced materials, 2017 - Wiley Online Library
Radiation therapy (RT) including external beam radiotherapy (EBRT) and internal
radioisotope therapy (RIT) has been widely used for clinical cancer treatment. However …

Albumin-bound formulation of paclitaxel (Abraxane® ABI-007) in the treatment of breast cancer

E Miele, GP Spinelli, E Miele, F Tomao… - International journal of …, 2009 - Taylor & Francis
Breast cancer is the most common type of malignancy diagnosed in women. In the
metastatic setting this disease is still uncurable. Taxanes represent an important class of …

On the latest three‐stage development of nanomedicines based on upconversion nanoparticles

W Fan, W Bu, J Shi - Advanced Materials, 2016 - Wiley Online Library
Following the “detect‐to‐treat” strategy, by biological engineering, the emerging
upconversion nanoparticles (UCNPs) have become one of the most promising inorganic …

Radiation effects on the tumor microenvironment: Implications for nanomedicine delivery

S Stapleton, D Jaffray, M Milosevic - Advanced drug delivery reviews, 2017 - Elsevier
The tumor microenvironment has an important influence on cancer biological and clinical
behavior and radiation treatment (RT) response. However, RT also influences the tumor …

Nanoparticle Albumin-Bound Paclitaxel: A Novel Cremphor-EL®-Free Formulation of Paclitaxel

TE Stinchcombe - Nanomedicine, 2007 - Taylor & Francis
Standard formulation paclitaxel requires the use of solvents, such as Cremphor-EL®, which
contribute to some of the toxicities commonly associated with paclitaxel-based therapy …

Advances of nanomedicine in radiotherapy

W Liu, B Chen, H Zheng, Y Xing, G Chen, P Zhou… - Pharmaceutics, 2021 - mdpi.com
Radiotherapy (RT) remains one of the current main treatment strategies for many types of
cancer. However, how to improve RT efficiency while reducing its side effects is still a large …

Nanoparticles for radiooncology: Mission, vision, challenges

LA Kunz-Schughart, A Dubrovska, C Peitzsch, A Ewe… - Biomaterials, 2017 - Elsevier
Cancer is one of the leading non-communicable diseases with highest mortality rates
worldwide. About half of all cancer patients receive radiation treatment in the course of their …

Nanomaterials for radiotherapeutics-based multimodal synergistic cancer therapy

X Yang, L Gao, Q Guo, Y Li, Y Ma, J Yang, C Gong… - Nano Research, 2020 - Springer
Over the past decade, numerous studies have attempted to enhance the effectiveness of
radiotherapy (external beam radiotherapy and internal radioisotope therapy) for cancer …