Growth hormone treatment for non-GHD disorders: Excitement tempered by biology

A Grimberg, CP Hawkes - The Journal of Clinical Endocrinology …, 2024 - academic.oup.com
The success of growth hormone (GH) replacement in children with classical GH deficiency
has led to excitement that other causes of short stature may benefit similarly. However …

[HTML][HTML] Reliability of agreement between insulin, clonidine, and glucagon stimulation tests for the diagnosis of growth hormone deficiency in children: a retrospective …

R Al Balwi, M Al-Qahtani, AK Alrowished, HA Shash… - Children, 2023 - mdpi.com
Growth hormone (GH) deficiency (GHD) is a rare disorder. The diagnosis of GHD requires a
combination of two provocative GH tests. This study aimed to find agreement between …

Puberty assessment and consideration of gonadotropin-releasing hormone agonists in transgender and gender-diverse youth

JY Lee - Pediatric annals, 2023 - journals.healio.com
Transgender and gender-diverse (TGD) youth may pursue gender-affirming medical therapy
in the form of gonadotropin-releasing hormone analogues (GnRHa), or “puberty blockers,” if …

[HTML][HTML] A proof-of-concept study of growth hormone in children with Phelan–McDermid syndrome

S Sethuram, T Levy, J Foss-Feig, D Halpern, S Sandin… - Molecular Autism, 2022 - Springer
Abstract Background Phelan–McDermid syndrome (PMS) is caused by 22q13 deletions
including SHANK3 or pathogenic sequence variants in SHANK3 and is among the more …

[HTML][HTML] Displasias esquelé ticas en endocrinologÃa pediá trica: perspectiva clÃnica y gené tica Skeletal dysplasias in paediatric endocrinology: a clinical and …

KE Heath, LÃS Montanà- Rev Esp Endocrinol …, 2022 - endocrinologiapediatrica.org
Las displasias esqueléticas constituyen un grupo de enfermedades de origen genético
caracterizadas por la organización anormal del tejido óseo y cartilaginoso. De especial …

[HTML][HTML] Clinical Features of Transient Growth Hormone Deficiency

Y Sakai, K Ikegawa, K Shimura, Y Hasegawa - Endocrines, 2023 - mdpi.com
Background: Most patients with idiopathic growth hormone deficiency (iGHD) in childhood
have normal GH stimulation test results in adulthood. The present study aimed to investigate …

[PDF][PDF] Growth hormone treatment for non-GHD disorders: Excitement

A Grimberg, CP Hawkes - 2023 - cora.ucc.ie
The success of growth hormone (GH) replacement in children with classical GH deficiency
has led to excitement that other causes of short stature may benefit similarly. However …

Commentary on “Growth plate extracellular matrix defects and short stature in children”

SY Kim - Annals of Pediatric Endocrinology & Metabolism, 2022 - e-apem.org
A growth plate is a location of linear growth [1]. The pathophysiology of impaired
chondrogenesis and differentiation in osteocyte alignment of children with short stature were …