[HTML][HTML] Androgen receptor gene pathway upregulation and radiation resistance in oligometastatic prostate cancer

H Saxby, S Boussios, C Mikropoulos - International Journal of Molecular …, 2022 - mdpi.com
Stereotactic ablative body radiotherapy (SABR) is currently used as a salvage intervention
for men with oligometastatic prostate cancer (PC), and increasingly so since the results of …

Approaches for boosting antitumor immunity in prostate cancer therapy: A comprehensive review on drugs, products, and nanoparticles

D Chen, Y Hu - Journal of Drug Delivery Science and Technology, 2023 - Elsevier
Prostate cancers are among the common malignancies in men. Despite the availability of
various treatment options, including chemotherapy, radiotherapy, and surgery, the prognosis …

Fate and state transitions during human blood vessel organoid development

MT Nikolova, Z He, RA Wimmer, M Seimiya, JM Nikoloff… - bioRxiv, 2022 - biorxiv.org
Blood vessel organoids (BVOs) derived from human pluripotent stem cells have emerged as
a novel system to understand human vascular development, model disorders, and develop …

Targeting HIF-1 for prostate cancer: A synthesis of preclinical evidence

Y Zohar, NJ Mabjeesh - Expert Opinion on Therapeutic Targets, 2023 - Taylor & Francis
Introduction Hypoxia-inducible factor (HIF) mediates multiple intracellular processes that
drive cellular metabolism and induce proliferation. Dysregulated HIF expression is …

[HTML][HTML] Deep learning-based automated pipeline for blood vessel detection and distribution analysis in multiplexed prostate cancer images

GM Karageorgos, S Cho, E McDonough… - Frontiers in …, 2024 - frontiersin.org
Introduction: Prostate cancer is a highly heterogeneous disease, presenting varying levels of
aggressiveness and response to treatment. Angiogenesis is one of the hallmarks of cancer …

SRF inhibitors reduce prostate cancer cell proliferation through cell cycle arrest in an isogenic model of castrate-resistant prostate cancer

H Azam, S Maher, S Clarke, WM Gallagher… - Cell Cycle, 2023 - Taylor & Francis
Castrate-resistant prostate cancer (CRPC) is challenging to treat, despite improvements with
next-generation anti-androgens such as enzalutamide, due to acquired resistance. One of …

[HTML][HTML] KIF11: A potential prognostic biomarker for predicting bone metastasis‑free survival of prostate cancer

H Wang, S Li, B Liu, S Wei, T Wang… - Oncology …, 2022 - spandidos-publications.com
Most prostate cancer (PCa) cases remain indolent with a relatively good prognosis.
However, bone metastasis of PCa can quickly worsen prognoses and lead to mortality …

Renal Cell Cancer–Insights in Drug Resistance Mechanisms

H Aweys, D Lewis, M Sheriff, RD Rabbani… - Anticancer …, 2023 - ar.iiarjournals.org
Renal cell carcinoma (RCC) is the prevalent form of kidney cancer in adults, with clear cell
renal carcinoma (ccRCC) being the predominant subtype. While surgical resection remains …

[HTML][HTML] Baicalein Relieves Ferroptosis-Mediated Phagocytosis Inhibition of Macrophages in Ovarian Endometriosis

ZH Yi, SQ Li, JY Ke, Y Wang, MZ Zhao, J Li… - Current Issues in …, 2022 - mdpi.com
Iron overload and oxidative stress have been reported to contribute to ferroptosis in
endometriotic lesions. However, the possible roles of iron overload on macrophages in …

[PDF][PDF] Prognostic value of genomic mutations in metastatic prostate cancer

H Zhu, Y Ding, H Huang, Q Lin, W Chen, Z Yu - Heliyon, 2023 - cell.com
Metastatic prostate cancer (mPC) has a poor prognosis, and new treatment strategies are
currently being offered for patients in clinical practice, but mPC is still incurable. A …