[HTML][HTML] The efficacy and safety of PARP inhibitors in mCRPC with HRR mutation in second-line treatment: a systematic review and bayesian network meta-analysis

Q Zhu, J Chen, H Liu, J Zhao, C Xu, G Sun, H Zeng - BMC cancer, 2024 - ncbi.nlm.nih.gov
Background Poly (ADP-ribose) polymerase inhibitors (PARPi) has been increasingly
adopted for metastatic castration-resistance prostate cancer (mCRPC) patients with …

[HTML][HTML] Overcoming the therapeutic resistance of hepatomas by targeting the tumor microenvironment

J Zhang, H Han, L Wang, W Wang, M Yang… - Frontiers in …, 2022 - frontiersin.org
Hepatocellular carcinoma accounts for the majority proportion of primary liver cancer and it
is the fourth leading cause of cancer-related mortality in the world, while multifactorial drug …

Unveiling the Chemistry of Citrus Peel: Insights into Nutraceutical Potential and Therapeutic Applications

H Munir, S Yaqoob, KA Awan, A Imtiaz, H Naveed… - Foods, 2024 - mdpi.com
The recent millennium has witnessed a notable shift in consumer focus towards natural
products for addressing lifestyle-related disorders, driven by their safety and cost …

miR-145-5p: a potential biomarker in predicting gleason upgrading of prostate biopsy samples scored 3+ 3= 6

T Wang, L Dong, J Sun, J Shao, J Zhang… - Cancer Management …, 2021 - Taylor & Francis
Background The Gleason grading system is a major tool used for prediction of prostate
cancer (PCa) behavior. Because of heterogeneity and sampling errors, prognosis is variable …

Prostate cancer-what about oligometastatic disease and stereotactic ablative radiotherapy?-a narrative review.

C Mikropoulos, H Saxby, S Boussios - Annals of palliative medicine, 2023 - kar.kent.ac.uk
Oligometastatic prostate cancer (OMPC) encompasses a heterogenous group of clinical
entities defined by the timing of the development of metastases. These include de novo …

Nanotherapy to Reshape the Tumor Microenvironment: A New Strategy for Prostate Cancer Treatment

J Deng, S Yuan, W Pan, Q Li, Z Chen - ACS Omega, 2024 - ACS Publications
Prostate cancer (PCa) is the second most common cancer in males worldwide. Androgen
deprivation therapy (ADT) is the primary treatment method used for PCa. Although more …

Ion Channels in Endometrial Cancer

BP Costa, FB Nunes, FC Noal, G Branchini - Cancers, 2022 - mdpi.com
Simple Summary Uterine or endometrial cancer is one of the most common types of cancer
among the female population. Different alterations of molecules are related to many types of …

[HTML][HTML] PARVB promotes malignant melanoma progression and is enhanced by hypoxic conditions

T Wang, Z Wu, Y Bi, Y Wang, C Zhao, H Sun, Z Wu… - Translational …, 2024 - Elsevier
Beta-Parvin (PARVB) is an actin-binding protein with functionality in extracellular matrix
binding. Recent studies suggest its potential as a biomarker for various cancers, given its …

The Application of Radiomics and AI to Molecular Imaging for Prostate Cancer

W Tapper, G Carneiro, C Mikropoulos… - Journal of personalized …, 2024 - mdpi.com
Molecular imaging is a key tool in the diagnosis and treatment of prostate cancer (PCa).
Magnetic Resonance (MR) plays a major role in this respect with nuclear medicine imaging …

[HTML][HTML] Bevacizumab increases the sensitivity of olaparib to homologous recombination-proficient ovarian cancer by suppressing CRY1 via PI3K/AKT pathway

Y Iida, N Yanaihara, Y Yoshino, M Saito… - Frontiers in …, 2024 - ncbi.nlm.nih.gov
PARP inhibitors have changed the management of advanced high-grade epithelial ovarian
cancer (EOC), especially homologous recombinant (HR)-deficient advanced high-grade …