Somatosensory and autonomic neuronal regulation of the immune response

S Udit, K Blake, IM Chiu - Nature Reviews Neuroscience, 2022 - nature.com
Bidirectional communication between the peripheral nervous system (PNS) and the immune
system is a crucial part of an effective but balanced mammalian response to invading …

The impact of heat stress on the immune system in dairy cattle: A review

M Bagath, G Krishnan, C Devaraj, VP Rashamol… - Research in veterinary …, 2019 - Elsevier
Heat stress is well documented to have a negative influence on livestock productivity and
these impacts may be exacerbated by climate change. Dairy cattle can be more vulnerable …

Inflammation–nature's way to efficiently respond to all types of challenges: implications for understanding and managing “the epidemic” of chronic diseases

JM Bennett, G Reeves, GE Billman… - Frontiers in …, 2018 - frontiersin.org
Siloed or singular system approach to disease management is common practice,
developing out of traditional medical school education. Textbooks of medicine describe a …

Diurnal cortisol slopes and mental and physical health outcomes: A systematic review and meta-analysis

EK Adam, ME Quinn, R Tavernier, MT McQuillan… - …, 2017 - Elsevier
Abstract Changes in levels of the stress-sensitive hormone cortisol from morning to evening
are referred to as diurnal cortisol slopes. Flatter diurnal cortisol slopes have been proposed …

Mechanisms and therapeutic relevance of neuro-immune communication

SS Chavan, VA Pavlov, KJ Tracey - Immunity, 2017 - cell.com
Active research at the frontiers of immunology and neuroscience has identified multiple
points of interaction and communication between the immune system and the nervous …

Molecular and functional neuroscience in immunity

VA Pavlov, SS Chavan, KJ Tracey - Annual review of …, 2018 - annualreviews.org
The nervous system regulates immunity and inflammation. The molecular detection of
pathogen fragments, cytokines, and other immune molecules by sensory neurons generates …

Corticosteroids: mechanisms of action in health and disease

S Ramamoorthy, JA Cidlowski - Rheumatic Disease …, 2016 - rheumatic.theclinics.com
Corticosteroids are a class of steroid hormones released by the adrenal cortex, which
includes glucocorticoids and mineralocorticoids. 1 However, the term “corticosteroids” is …

Stress–glucocorticoid–TSC22D3 axis compromises therapy-induced antitumor immunity

H Yang, L Xia, J Chen, S Zhang, V Martin, Q Li, S Lin… - Nature medicine, 2019 - nature.com
Psychological distress has long been suspected to influence cancer incidence and mortality.
It remains largely unknown whether and how stress affects the efficacy of anticancer …

Neuroimmune interactions in peripheral organs

RGJ Klein Wolterink, GS Wu, IM Chiu… - Annual review of …, 2022 - annualreviews.org
Interactions between the nervous and immune systems were recognized long ago, but
recent studies show that this crosstalk occurs more frequently than was previously …

Adverse childhood experiences and trauma informed care: the future of health care

R Oral, M Ramirez, C Coohey, S Nakada, A Walz… - Pediatric …, 2016 - nature.com
Adverse childhood experiences (ACEs) are related to short-and long-term negative physical
and mental health consequences among children and adults. Studies of the last three …