Polyphenols and neuroprotection: Therapeutic implications for cognitive decline

G Caruso, SA Torrisi, MP Mogavero, W Currenti… - Pharmacology & …, 2022 - Elsevier
Dietary polyphenols have been the focus of major interest for their potential benefits on
human health. Several preclinical studies have been conducted to provide a rationale for …

Dietary anti-aging polyphenols and potential mechanisms

J Luo, H Si, Z Jia, D Liu - Antioxidants, 2021 - mdpi.com
For years, the consumption of a diet rich in fruits and vegetables has been considered
healthy, increasing longevity, and decreasing morbidities. With the assistance of basic …

Recent advances in research on polyphenols: effects on microbiota, metabolism, and health

HN Rajha, A Paule, G Aragonès… - Molecular Nutrition & …, 2022 - Wiley Online Library
Polyphenols have attracted huge interest among researchers of various disciplines because
of their numerous biological activities, such as antioxidative, antiinflammatory, antiapoptotic …

Tetrahydroxy stilbene glycoside ameliorates Alzheimer's disease in APP/PS1 mice via glutathione peroxidase related ferroptosis

Y Gao, J Li, Q Wu, S Wang, S Yang, X Li… - International …, 2021 - Elsevier
Amyloid beta peptide (Aβ) has been confirmed to be an essential reason of Alzheimer's
disease (AD) for a long time. Ferroptosis is a newly recognized oxidative cell death …

Effects of urolithin A on mitochondrial parameters in a cellular model of early Alzheimer disease

C Esselun, E Theyssen, GP Eckert - International journal of molecular …, 2021 - mdpi.com
(1) Background: Ellagitannins are natural products occurring in pomegranate and walnuts.
They are hydrolyzed in the gut to release ellagic acid, which is further metabolized by the …

Olea europaea L-derived secoiridoids: Beneficial health effects and potential therapeutic approaches

S Filardo, M Roberto, D Di Risola, L Mosca… - Pharmacology & …, 2024 - Elsevier
Over the years, health challenges have become increasingly complex and global and, at the
beginning of the 21st century, chronic diseases, including cardiovascular, neurological, and …

Role of hydroxytyrosol and oleuropein in the prevention of aging and related disorders: focus on neurodegeneration, skeletal muscle dysfunction and gut microbiota

L Micheli, L Bertini, A Bonato, N Villanova, C Caruso… - Nutrients, 2023 - mdpi.com
Aging is a multi-faceted process caused by the accumulation of cellular damage over time,
associated with a gradual reduction of physiological activities in cells and organs. This …

Searching for the antioxidant, anti-inflammatory, and neuroprotective potential of natural food and nutritional supplements for ocular health in the mediterranean …

M Valero-Vello, C Peris-Martínez, JJ García-Medina… - Foods, 2021 - mdpi.com
Adherence to a healthy diet offers a valuable intervention to compete against the increasing
cases of ocular diseases worldwide, such as dry eye disorders, myopia progression …

Phenolic compounds from virgin olive oil: Approaches for their synthesis and analogues

BT Martins, MR Bronze, MR Ventura - Journal of Agricultural and …, 2022 - ACS Publications
Virgin olive oil (VOO) is the main fat consumed by populations in the Mediterranean basin,
and phenolic compounds, minor components of this fat, are known to be responsible for …

Walnut oil reduces Aβ levels and increases neurite length in a cellular model of early Alzheimer disease

C Esselun, F Dieter, N Sus, J Frank, GP Eckert - Nutrients, 2022 - mdpi.com
(1) Background: Mitochondria are the cells' main source of energy. Mitochondrial
dysfunction represents a key hallmark of aging and is linked to the development of …