Induced tolerogenic dendritic cells are a powerful immunotherapy for autoimmune disease
that have shown promise in laboratory models of disease and early clinical trials. In contrast …

The immune system functions in a sexually dimorphic manner, with females exhibiting more
robust immune responses than males. However, how female sex hormones affect immune …

Transdermal drug delivery systems have become an intriguing research topic in
pharmaceutical technology area and one of the most frequently developed pharmaceutical …

Cancer vaccines targeting patient-specific neoantigens have emerged as a promising
strategy for improving responses to immune checkpoint blockade. However, neoantigenic …

Patients suffering from alopecia areata (AA) can lose hair in focal regions, the complete
scalp, including eyelashes and eyebrows, or even the entire body. The exact pathology is …

The interaction between T cell and dendritic cells (DCs) that leads to T cell activation affects
the progression of the immune response including autoimmune diseases. Antigen …

Dendritic cells (DC) are professional antigen presenting cells comprising a variety of
subsets, as either resident or migrating cells, in lymphoid and non-lymphoid organs. In the …

Dendritic cells (DCs) are a heterogeneous population playing a pivotal role in immune
responses and tolerance. DCs promote immune tolerance by participating in the negative …

The development of cancer neoantigen vaccines that prime the anti-tumor immune
responses has been hindered in part by challenges in delivery of neoantigens to the tumor …

As potent antigen-presenting cells, dendritic cells (DCs) comprise the most heterogeneous
cell population with significant cellular phenotypic and functional plasticity. They form a …